A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection
Sign Up to like & getrecommendations! Published in 2022 at "Cell Reports"
DOI: 10.1016/j.celrep.2022.110368
Abstract: Emerging evidence indicate that both neutralizing and Fc-mediated effector functions of antibodies contribute to protection against SARS-CoV-2. It is unclear if Fc-effector functions alone can protect against SARS-CoV-2. Here, we isolated CV3-13, a non-neutralizing antibody,… read more here.
Keywords: sars cov; non neutralizing; delays virus; neutralizing antibody ... See more keywords
Bluetongue virus spread in Europe is a consequence of climatic, landscape and vertebrate host factors as revealed by phylogeographic inference
Sign Up to like & getrecommendations! Published in 2017 at "Proceedings of the Royal Society B: Biological Sciences"
DOI: 10.1098/rspb.2017.0919
Abstract: Spatio-temporal patterns of the spread of infectious diseases are commonly driven by environmental and ecological factors. This is particularly true for vector-borne diseases because vector populations can be strongly affected by host distribution as well… read more here.
Keywords: virus spread; climatic landscape; landscape; host ... See more keywords
Twenty years of West Nile virus spread and evolution in the Americas visualized by Nextstrain
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1008042
Abstract: It has been 20 years since West Nile virus first emerged in the Americas, and since then, little progress has been made to control outbreaks caused by this virus. After its first detection in New… read more here.
Keywords: west nile; spread evolution; nile virus; virus spread ... See more keywords
Memory CD8 T Cells Protect against Cytomegalovirus Disease by Formation of Nodular Inflammatory Foci Preventing Intra-Tissue Virus Spread
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14061145
Abstract: Cytomegaloviruses (CMVs) are controlled by innate and adaptive immune responses in an immunocompetent host while causing multiple organ diseases in an immunocompromised host. A risk group of high clinical relevance comprises transiently immunocompromised recipients of… read more here.
Keywords: virus; cd8 cells; virus spread; tissue ... See more keywords