Human papilloma virus vaccine and VITT antibody induction
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26659
Abstract: We recently reported on a 25-year-old female without a history of heparin exposure, presenting with thrombocytopenia, thrombosis, and elevated D-dimer levels 10 days after nine-valent human papillo-mavirus (HPV) vaccination ( Gardasil , Merck and Co).… read more here.
Keywords: vitt; vaccine vitt; papilloma virus; human papilloma ... See more keywords
Purification processes of live virus vaccine candidates expressed in adherent Vero cell lines via multimodal chromatography in flowthrough mode.
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology and bioengineering"
DOI: 10.1002/bit.28430
Abstract: Live virus vaccine (LVV) purification, employing chromatography, can be challenged by low binding capacities and elution yields. Alternatively, processes relying solely on enzymatic digestion steps and size-based membrane separations can be limited by suboptimal reduction… read more here.
Keywords: purification; cell; live virus; chromatography ... See more keywords
Efficacy of the oral rabies virus vaccine strain SPBN GASGAS in foxes and raccoon dogs.
Sign Up to like & getrecommendations! Published in 2017 at "Vaccine"
DOI: 10.1016/j.vaccine.2017.09.093
Abstract: To test the immunogenicity and efficacy of a new oral rabies virus vaccine strain SPBN GASGAS in wildlife target species, one group of foxes and two groups of raccoon dogs were offered a bait containing… read more here.
Keywords: virus vaccine; rabies virus; oral rabies; raccoon dogs ... See more keywords
Enhancement of safety and immunogenicity of the Chinese Hu191 measles virus vaccine by alteration of the S-adenosylmethionine (SAM) binding site in the large polymerase protein
Sign Up to like & getrecommendations! Published in 2018 at "Virology"
DOI: 10.1016/j.virol.2018.02.022
Abstract: Abstract The live-attenuated measles virus (MV) vaccine based on the Hu191 strain has played a significant role in controlling measles in China. However, it has considerable adverse effects that may cause public health burden. We… read more here.
Keywords: virus vaccine; binding site; hu191; sam binding ... See more keywords
A recombinant measles virus vaccine strongly reduces SHIV viremia and virus reservoir establishment in macaques
Sign Up to like & getrecommendations! Published in 2021 at "npj Vaccines"
DOI: 10.1038/s41541-021-00385-6
Abstract: Replicative vectors derived from live-attenuated measles virus (MV) carrying additional non-measles vaccine antigens have long demonstrated safety and immunogenicity in humans despite pre-existing immunity to measles. Here, we report the vaccination of cynomolgus macaques with… read more here.
Keywords: virus vaccine; viremia; recombinant measles; measles virus ... See more keywords
Development of a downstream process for the production of an inactivated whole hepatitis C virus vaccine
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-72328-5
Abstract: There is a large unmet need for a prophylactic hepatitis C virus (HCV) vaccine to control the ongoing epidemic with this deadly pathogen. Many antiviral vaccines employ whole viruses as antigens. For HCV, this approach… read more here.
Keywords: virus vaccine; production; hepatitis virus; vaccine ... See more keywords
An Inactivated Influenza Virus Vaccine Approach to Targeting the Conserved Hemagglutinin Stalk and M2e Domains
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DOI: 10.3390/vaccines7030117
Abstract: Universal influenza virus vaccine candidates that focus on the conserved hemagglutinin (HA) stalk domain and the extracellular domain of the matrix protein 2 (M2e) have been developed to increase the breadth of protection against multiple… read more here.
Keywords: virus vaccine; influenza virus; hemagglutinin; m2e ... See more keywords
Hepatitis C Virus Vaccine: Challenges and Prospects
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DOI: 10.3390/vaccines8010090
Abstract: The hepatitis C virus (HCV) causes both acute and chronic infection and continues to be a global problem despite advances in antiviral therapeutics. Current treatments fail to prevent reinfection and remain expensive, limiting their use… read more here.
Keywords: virus vaccine; hepatitis virus; vaccine; virus ... See more keywords
Research Updates for Influenza Virus and Vaccine Development
Sign Up to like & getrecommendations! Published in 2021 at "Vaccines"
DOI: 10.3390/vaccines9040383
Abstract: While the scientific community has been focusing on combating novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is responsible for the current COVID-19 pandemic, we also want to draw your attention to this Special… read more here.
Keywords: virus vaccine; research updates; updates influenza; influenza virus ... See more keywords