Mechanoelectric coupling and arrhythmogenesis in cardiomyocytes contracting under mechanical afterload in a 3D viscoelastic hydrogel
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DOI: 10.1073/pnas.2108484118
Abstract: Significance The heart autoregulates its contractile strength to maintain cardiac output when pumping blood against the mechanical afterload from vascular resistance. Increased afterload in cardiovascular diseases is associated with cardiac arrhythmias. However, the underlying mechanisms… read more here.
Keywords: afterload; mechanical afterload; ca2; viscoelastic hydrogel ... See more keywords