Sub-visible Particles in IVIg Formulations Activate Complement in Human Serum.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2019.10.041
Abstract: When administered intravenously, various particles and nanomedicines activate complement, potentially leading to infusion reactions and other adverse drug reactions. Particles form within formulations of therapeutic proteins due to stresses incurred during shipping, handling and administration… read more here.
Keywords: human serum; activate complement; sub visible; visible particles ... See more keywords