Computational Mapping of Conformational Dynamics and Interaction Hotspots of Human VISTA with pH-Selective Antibodies.
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DOI: 10.1021/acs.biochem.4c00863
Abstract: The V-domain Ig suppressor of T-cell activation (VISTA) is a critical negative immune checkpoint protein that regulates T-cell-mediated anticancer immune responses, making it a promising target for immunotherapy. Unlike other checkpoint proteins, VISTA activity is… read more here.
Keywords: dynamics interaction; computational mapping; mapping conformational; vista selective ... See more keywords