Visualizing the three-metal-ion-dependent cleavage of a mutagenic nucleotide
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DOI: 10.1073/pnas.2207180119
Abstract: The accurate replication, transcription, and maintenance of genetic material requires housekeeping enzymes that prevent the spontaneous mutagenesis of DNA by catalyzing the removal of oxidized deoxynucleoside triphosphates (dNTPs). These include the Nudix hydrolase superfamily member… read more here.
Keywords: metal ion; visualizing three; mth1; oxo dgtp ... See more keywords