Articles with "vital organs" as a keyword



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Immune-mediated organ pathologies of vital organs

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Published in 2021 at "International Reviews of Immunology"

DOI: 10.1080/08830185.2021.1969795

Abstract: Microbial invasion triggers host defense responses to eliminate infection. Bacterial components such as lipopolysaccharides, peptidoglycan, and nucleic acid, and viral components such as viral coat proteins and nucleic acid can activate innate and adaptive immunity… read more here.

Keywords: gut; vital organs; article; infection ... See more keywords

Protective effects of lipid emulsion on vital organs through the LPS/TLR4 pathway in acute organophosphate poisoning

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Published in 2025 at "BMC Pharmacology & Toxicology"

DOI: 10.1186/s40360-025-00904-4

Abstract: Organophosphorus poisoning (OP), a prevalent form of pesticide intoxication, induces severe multiorgan dysfunction. While combined lipid emulsion (ILE) and standard treatment (pralidoxime methiodide & atropine) demonstrate improved clinical outcomes, the therapeutic mechanisms remain elusive. An… read more here.

Keywords: treatment; tlr4 pathway; emulsion; vital organs ... See more keywords

Pharmacological basis of bergapten in gastrointestinal diseases focusing on H+/K+ ATPase and voltage-gated calcium channel inhibition: A toxicological evaluation on vital organs

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.1005154

Abstract: Aim and objectives: This study aimed to establish a pharmacological basis for evaluating the effects of bergapten (5-methoxypsoralen) in gastrointestinal diseases and assessment of its toxicological profile. Methods: The pharmacokinetic profile was evaluated using the… read more here.

Keywords: gastrointestinal diseases; inhibition; vital organs; atpase ... See more keywords