VITALITY-ALS, a phase III trial of tirasemtiv, a selective fast skeletal muscle troponin activator, as a potential treatment for patients with amyotrophic lateral sclerosis: study design and baseline characteristics
Sign Up to like & getrecommendations! Published in 2018 at "Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration"
DOI: 10.1080/21678421.2018.1426770
Abstract: Abstract Objective: To assess the efficacy of tirasemtiv, a fast skeletal muscle troponin activator, vs. placebo on respiratory function and other functional measures in patients with amyotrophic lateral sclerosis (ALS). This study was designed to… read more here.
Keywords: muscle; vitality als; amyotrophic lateral; tirasemtiv ... See more keywords
Noninvasive ventilation use by patients enrolled in VITALITY-ALS
Sign Up to like & getrecommendations! Published in 2021 at "Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration"
DOI: 10.1080/21678421.2021.1904993
Abstract: Abstract Objectives: To evaluate the prescribing practices of noninvasive ventilation (NIV) and patient compliance during VITALITY-ALS. Methods: VITALITY-ALS enrolled patients with a slow vital capacity (SVC) ≥70% of predicted who were not using NIV at… read more here.
Keywords: prescribed niv; vitality; vitality als; noninvasive ventilation ... See more keywords