Determination of Vitamin E and its Metabolites in Equine Urine Using Liquid Chromatography - Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2021 at "Drug testing and analysis"
DOI: 10.1002/dta.3006
Abstract: Equine neuroaxonal dystrophy/degenerative myeloencephalopathy (eNAD/EDM) is a hereditary, deteriorating central nervous disease in horses. Currently, the only way to confirm eNAD/EDM is through a postmortem histological evaluation of the central nervous system. Vitamin E, specifically… read more here.
Keywords: enad edm; vitamin metabolites; metabolites equine; equine urine ... See more keywords
Use of surface plasmon resonance in the binding study of vitamin D, metabolites and analogues with vitamin D binding protein
Sign Up to like & getrecommendations! Published in 2017 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-017-0200-6
Abstract: AbstractVitamin D3 and its metabolites are lipophilic molecules with low aqueous solubility and must be transported bound to plasma carrier proteins, primarily to vitamin D binding protein (DBP). The biological functions of vitamin D3 metabolites… read more here.
Keywords: vitamin metabolites; vitamin binding; binding protein; vitamin ... See more keywords
Combinations of Vitamin A and Vitamin E Metabolites Confer Resilience against Amyloid-β Aggregation
Sign Up to like & getrecommendations! Published in 2023 at "ACS Chemical Neuroscience"
DOI: 10.1021/acschemneuro.2c00523
Abstract: Alzheimer’s disease is characterized by the presence in the brain of amyloid plaques formed by the aberrant deposition of the amyloid-β peptide (Aβ). Since many vitamins are dysregulated in this disease, we explored whether these… read more here.
Keywords: resilience; aggregation; vitamin metabolites; vitamin vitamin ... See more keywords
Unraveling the complex interplay between obesity and vitamin D metabolism
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-58154-z
Abstract: Vitamin D deficiency and obesity are a worldwide health issue. Obesity refers to the accumulation of excessive fats in the body which could lead to the development of diseases. Obese people have low vitamin D… read more here.
Keywords: vitamin metabolites; obesity; uhplc method; vitamin ... See more keywords
Changes in vitamin D metabolites at the time of critical illness and 6 months later—A prospective observational study
Sign Up to like & getrecommendations! Published in 2022 at "Acta Anaesthesiologica Scandinavica"
DOI: 10.1111/aas.14137
Abstract: Despite multiple studies suggesting that low 25(OH)D‐vitamin levels are associated with worse outcomes in critically ill individuals, attempts to mitigate the outcomes by fixed dose enteral supplementation unguided by baseline or target blood levels have… read more here.
Keywords: changes vitamin; time critical; metabolites time; vitamin metabolites ... See more keywords
Physiologically Based Pharmacokinetic Modeling of Vitamin D3 and Metabolites in Vitamin D–Insufficient Patients
Sign Up to like & getrecommendations! Published in 2022 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.121.000609
Abstract: A physiologically based pharmacokinetic (PBPK) model of vitamin D3 and metabolites [25(OH)D3, 1,25(OH)2D3, and 24,25(OH)2D3] is presented. In this study, patients with 25(OH)D3 plasma concentrations below 30 ng/ml were studied after a single dose of… read more here.
Keywords: physiologically based; based pharmacokinetic; vitamin metabolites; pbpk model ... See more keywords
Administration of Vitamin D Metabolites Affects RNA Expression of Xenobiotic Metabolising Enzymes and Function of ABC Transporters in Rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Chemistry"
DOI: 10.1155/2019/1279036
Abstract: From studies on different species and in cell culture systems, it has been suggested that vitamin D metabolites might affect the metabolism and elimination of xenobiotics. Although most studies performed on rodents and cell cultures… read more here.
Keywords: administration vitamin; vitamin metabolites; treatment; metabolites affects ... See more keywords
CYP3A4 mutation causes vitamin D–dependent rickets type 3
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Investigation"
DOI: 10.1172/jci98680
Abstract: Genetic forms of vitamin D–dependent rickets (VDDRs) are due to mutations impairing activation of vitamin D or decreasing vitamin D receptor responsiveness. Here we describe two unrelated patients with early-onset rickets, reduced serum levels of… read more here.
Keywords: vitamin dependent; vitamin metabolites; cyp3a4; dependent rickets ... See more keywords
Simultaneous quantification of vitamin E and vitamin E metabolites in equine plasma and serum using LC-MS/MS
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Veterinary Diagnostic Investigation"
DOI: 10.1177/10406387211005433
Abstract: Vitamin E deficiencies can impact normal growth and development in humans and animals, and assessment of circulating levels of vitamin E and its metabolites may be an important endpoint for evaluation. Development of a sensitive… read more here.
Keywords: vitamin; plasma serum; vitamin metabolites; quantification ... See more keywords
Vitamin D and Its Metabolites Deficiency in Acute Coronary Syndrome Patients Undergoing Coronary Angiography: A Case–Control Study
Sign Up to like & getrecommendations! Published in 2021 at "Vascular Health and Risk Management"
DOI: 10.2147/vhrm.s312376
Abstract: Background Vitamin D deficiency is considered an emerging health problem that affects at least one billion patients worldwide. Calcitriol 1,25(OH)2D3 has several systemic effects, including anti-inflammatory, anti-thrombotic and anti-atherosclerotic impacts that explain its cardioprotective effects.… read more here.
Keywords: acs; vitamin metabolites; coronary angiography; undergoing coronary ... See more keywords
Evaluation of serum vitamin D metabolites, phagocytosis, and biomarkers of inflammation in dogs with naturally occurring diabetes mellitus
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2024.1441993
Abstract: Naturally occurring diabetes mellitus (NODM) is one of the most common endocrine disorders in dogs and its etiology closely resembles type 1 diabetes mellitus (T1DM) in people. Human patients with T1DM commonly have cellular derangements… read more here.
Keywords: naturally occurring; vitamin metabolites; serum; diabetes mellitus ... See more keywords