Activation of Vitamin D/VDR Signaling Reverses Gemcitabine Resistance of Pancreatic Cancer Cells Through Inhibition of MUC1 Expression.
Sign Up to like & getrecommendations! Published in 2022 at "Digestive diseases and sciences"
DOI: 10.1158/1538-7445.am2022-6367
Abstract: BACKGROUND Pancreatic ductal adenocarcinoma (PDA) has a poor prognosis due to its therapeutic resistance. Inactivation of vitamin D/vitamin D receptor (VDR) signaling may contribute to the malignant phenotype of PDA and altered expression of oncoprotein… read more here.
Keywords: vitamin vdr; expression; resistance; vdr signaling ... See more keywords
Women with recurrent spontaneous abortion have decreased 25(OH) vitamin D and VDR at the fetal-maternal interface
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DOI: 10.1590/1414-431x20176527
Abstract: Immunological mechanisms have been proposed to underlie the pathogenesis of recurrent spontaneous abortion (RSA). Vitamin D has a potent immunomodulatory effect, which may affect pregnancy outcome. The objective of this study was to investigate 25-hydroxyvitamin… read more here.
Keywords: recurrent spontaneous; spontaneous abortion; abortion; vitamin vdr ... See more keywords
Vitamin D–VDR Novel Anti-Inflammatory Molecules—New Insights into Their Effects on Liver Diseases
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DOI: 10.3390/ijms23158465
Abstract: There is consistent evidence that vitamin D deficiency is strongly associated with liver dysfunction, disease severity, and poor prognosis in patients with liver disease. Vitamin D and its receptor (VDR) contribute to the regulation of… read more here.
Keywords: liver disease; vitamin; vitamin vdr; liver diseases ... See more keywords