Nivolumab-associated vitiligo-like depigmentation in a patient with acute myeloid leukemia: A novel finding
Sign Up to like & getrecommendations! Published in 2017 at "JAAD Case Reports"
DOI: 10.1016/j.jdcr.2016.10.008
Abstract: Programmed cell death–1 receptor (PD-1) inhibitors enhance the antitumoral immune response via immune checkpoint inhibition. In a healthy immune system, the binding of ligands to PD-1 induces T-cell inactivation and prevents overactive immune responses. However,… read more here.
Keywords: like depigmentation; depigmentation patient; patient acute; vitiligo like ... See more keywords
Vitiligo-like lesions in a patient treated with nivolumab for renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Medicine"
DOI: 10.1097/md.0000000000013810
Abstract: Rationale: The introduction of immune check-point inhibitors (ICIs) in the treatment of solid neoplasms is associated with the need to know and manage a new type of side effects that are commonly defined immune-mediated adverse… read more here.
Keywords: like lesions; cell carcinoma; renal cell; vitiligo like ... See more keywords
Vitiligo-Like Depigmentation following Treatment with Imiquimod 5% Cream for Condylomata Acuminata
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DOI: 10.1159/000510736
Abstract: Imiquimod cream is an immunomodulatory agent that has been approved by the US Food and Drug Administration for use in the treatment of anogenital warts (condylomata acuminata) due to its local immune effects in activating… read more here.
Keywords: condylomata acuminata; like depigmentation; depigmentation following; vitiligo like ... See more keywords
Nivolumab induced vitiligo-like lesions in a patient with metastatic squamous cell carcinoma of the lung.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of thoracic disease"
DOI: 10.21037/jtd.2018.05.104
Abstract: Nivolumab, a fully humanized monoclonal IgG4 antibody blocking programmed cell death-1 (PD-1), has demonstrated improved survival over docetaxel in previously treated patients with advanced non-small cell lung cancer (NSCLC) (1,2). Vitiligo-like depigmentation is a well… read more here.
Keywords: induced vitiligo; like lesions; nivolumab induced; vitiligo like ... See more keywords
Clinical Presentation and Prognostic Features in Patients with Immunotherapy-Induced Vitiligo-like Depigmentation: A Monocentric Prospective Observational Study
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DOI: 10.3390/cancers14194576
Abstract: Simple Summary In this study, we thoroughly explore the clinical and biological features of immunotherapy-induced vitiligo-like depigmentation (VLD) in patients with stage III-IV melanoma receiving immunotherapy. Key findings include a distinct immune signature with an… read more here.
Keywords: vitiligo like; vld; like depigmentation; cpi ... See more keywords