Long‐term outcomes of combined intravitreal methotrexate and systemic high‐dose methotrexate therapy in vitreoretinal lymphoma
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DOI: 10.1002/cam4.5609
Abstract: The optimal treatment for vitreoretinal lymphoma (VRL) remains a challenge, as central nervous system (CNS) relapse occurs frequently, leading to the worst impact on survival. We previously proposed combined intravitreal methotrexate and systemic high‐dose methotrexate… read more here.
Keywords: combined intravitreal; vitreoretinal lymphoma; systemic high; methotrexate ... See more keywords
Logistic regression models of cytokines in differentiating vitreoretinal lymphoma from uveitis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24689
Abstract: Vitreoretinal lymphoma (VRL) can commonly masquerade as chronic idiopathic uveitis due to its nonspecific clinical presentation. Thus, its early diagnosis is difficult. In this study, new logistic regression models were used to classify VRL and… read more here.
Keywords: uveitis; logistic regression; lymphoma; vitreoretinal lymphoma ... See more keywords
Vitreoretinal Lymphoma: Optimizing Diagnostic Yield and Accuracy.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2021.09.032
Abstract: PURPOSE To determine whether the addition of adjunctive tests, including immunohistochemistry [IHC], cytokine analysis, flow cytometry, and IgH gene rearrangement testing, achieves improved diagnostic parameters compared to cytologic smears alone in the detection of vitreoretinal… read more here.
Keywords: lymphoma; protocol; diagnostic yield; vitreoretinal lymphoma ... See more keywords
Vitreoretinal lymphoma: an alternative view
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DOI: 10.1038/s41433-021-01841-2
Abstract: TO THE EDITOR: I commend Hearne et al on their effort to raise awareness of vitreoretinal lymphoma (VRL) [1]. However, I respectfully disagree with the authors’ interpretation of the term ‘primary’, which implies that the… read more here.
Keywords: lymphoma; term; disease; alternative view ... See more keywords
Vitreous levels of interleukin-35 as a prognostic factor in B-cell vitreoretinal lymphoma
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DOI: 10.1038/s41598-020-72962-z
Abstract: Vitreoretinal lymphoma (VRL) is a rare disease of B-cell origin with poor prognosis. Regulatory cytokines promote tumor development by suppressing antitumor immunity in several cancer types, including B-cell malignancies. To identify the regulatory cytokines associated… read more here.
Keywords: poor prognosis; regulatory cytokines; vitreoretinal lymphoma; patients vrl ... See more keywords
Immunohistochemical and Immunocytochemical Analyses in Patients with Vitreoretinal Lymphoma
Sign Up to like & getrecommendations! Published in 2018 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2018.1533984
Abstract: ABSTRACT Purpose: The aim of this study was to analyze immunohistochemical and immunocytological findings by examining enucleated eyes and vitreous cell block (CB) in patients with vitreoretinal lymphoma (VRL). Methods: Histological specimens were obtained from… read more here.
Keywords: enucleated eyes; immunocytochemical analyses; lymphoma cells; immunohistochemical immunocytochemical ... See more keywords
Development of Vitreoretinal Lymphoma in a Patient with Sarcoid Uveitis
Sign Up to like & getrecommendations! Published in 2019 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2019.1605452
Abstract: ABSTRACT Purpose The purpose of this article is to report the first case of primary vitreoretinal lymphoma in a patient with sarcoid uveitis. Material and Methods A 63-year-old woman with biopsy-proven sarcoid uveitis diagnosed 7… read more here.
Keywords: lymphoma patient; sarcoid uveitis; lymphoma; vitreoretinal lymphoma ... See more keywords
Serial Detection of MYD88 L265P Mutation in the Aqueous Humor of a Patient with Vitreoretinal Lymphoma for Disease Monitoring
Sign Up to like & getrecommendations! Published in 2020 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2020.1802488
Abstract: ABSTRACT Purpose To report a case of a patient whose MYD88 mutation disappeared from the aqueous humor following treatment with intravitreal methotrexate. Methods A retrospective review of clinical, histopathological and imaging records. Results A 49-year-old… read more here.
Keywords: myd88 l265p; l265p mutation; mutation; vitreoretinal lymphoma ... See more keywords
Consensus Recommendations for the Diagnosis of Vitreoretinal Lymphoma
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DOI: 10.1080/09273948.2021.1878233
Abstract: ABSTRACT Purpose To provide recommendations for diagnosis of vitreoretinal lymphoma (VRL). Methods Literature was reviewed for reports supporting the diagnosis of VRL. A questionnaire (Delphi 1 round) was distributed to 28 participants. In the second… read more here.
Keywords: diagnosis vitreoretinal; consensus; consensus recommendations; recommendations diagnosis ... See more keywords
Clinical Outcomes in Vitrectomized versus Non-vitrectomized Eyes in Patients with Primary Vitreoretinal Lymphoma
Sign Up to like & getrecommendations! Published in 2022 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2022.2033794
Abstract: ABSTRACT Aim To evaluate if there is a difference in the clinical course of primary vitreoretinal lymphoma (PVRL) in vitrectomized versus non-vitrectomized eyes. Methods Observational multicenter retrospective case series of patients diagnosed with PVRL between… read more here.
Keywords: vitrectomized eyes; non vitrectomized; vitreoretinal lymphoma; versus non ... See more keywords
Vitreoretinal Lymphoma in a Patient with Rheumatoid Arthritis with a History of Methotrexate-associated Lymphoproliferative Disorders.
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DOI: 10.1080/09273948.2022.2144384
Abstract: Methotrexate (MTX) may induce immunosuppression and facilitate the onset of lymphoproliferative disorders (LPD). Most cases of MTX-LPD occur in patients with rheumatoid arthritis; the incidence is high in Japan. Vitreoretinal lymphoma (VRL) is a rare… read more here.
Keywords: vitreoretinal lymphoma; mtx; rheumatoid arthritis; methotrexate ... See more keywords