Thyroid‐on‐a‐Chip: An Organoid Platform for In Vitro Assessment of Endocrine Disruption
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201555
Abstract: Thyroid is a glandular tissue in the human body in which the function can be severely affected by endocrine disrupting chemicals (EDCs). Current in vitro assays to test endocrine disruption by chemical compounds are largely… read more here.
Keywords: vitro; chip; endocrine disruption; thyroid chip ... See more keywords
Biomimetic In Vitro Lung Models: Current Challenges and Future Perspective
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DOI: 10.1002/adma.202210519
Abstract: As post‐COVID complications, chronic respiratory diseases are one of the foremost causes of mortality. The quest for a cure for this recent global challenge underlines that the lack of predictive in vitro lung models is… read more here.
Keywords: vitro; lung models; models current; biomimetic vitro ... See more keywords
An In Vitro Mat‐on‐Gel Construct for Engineering Cardiac Tissue
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DOI: 10.1002/admi.202100341
Abstract: Topographical and mechanical features are two key factors for cell development. Here, an easy‐to‐make Mat‐on‐Gel construct is introduced to study the co‐effects of nanogeometry and stiffness on cardiomyocyte (CM) functional development in vitro. The construct… read more here.
Keywords: gel construct; mat gel; gel; vitro ... See more keywords
Emerging Three‐Dimensional Integrated Systems for Biomimetic Neural In Vitro Cultures
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DOI: 10.1002/admi.202101297
Abstract: 3D in vitro neural cultures have gained interest in recent years as promising biomimetic micro‐environments which can regulate cell response to neural guidance cues. Several bioengineered technologies have been developed in combination with biomaterials to… read more here.
Keywords: vitro; cell; dimensional integrated; integrated systems ... See more keywords
Lipid Nanoparticles Deliver the Therapeutic VEGFA mRNA In Vitro and In Vivo and Transform Extracellular Vesicles for Their Functional Extensions
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DOI: 10.1002/advs.202206187
Abstract: Lipid nanoparticles (LNPs) are currently used to transport functional mRNAs, such as COVID‐19 mRNA vaccines. The delivery of angiogenic molecules, such as therapeutic VEGF‐A mRNA, to ischemic tissues for producing new blood vessels is an… read more here.
Keywords: vitro; extracellular vesicles; mrna; vegf mrna ... See more keywords
Millimeter-Wave Heating in In Vitro Studies: Effect of Convection in Continuous and Pulse-Modulated Regimes.
Sign Up to like & getrecommendations! Published in 2019 at "Bioelectromagnetics"
DOI: 10.1002/bem.22223
Abstract: Shallow penetration of millimeter waves (MMW) and non-uniform illumination in in vitro experiments result in a non-uniform distribution of the specific absorption rate (SAR). These SAR gradients trigger convective currents in liquids affecting transient and… read more here.
Keywords: temperature; effect convection; convection; modulated regimes ... See more keywords
Shuttle‐mediated nanoparticle transport across an in vitro brain endothelium under flow conditions
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26221
Abstract: The blood brain barrier (BBB) represents a challenge in the development of new nano‐delivery systems able to reach the central nervous system (CNS). In order to test the efficacy of these nanocarriers, it is fundamental… read more here.
Keywords: transport; shuttle mediated; vitro; flow conditions ... See more keywords
Microfluidic platforms for the study of neuronal injury in vitro
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26519
Abstract: Traumatic brain injury (TBI) affects 5.3 million people in the United States, and there are 12,500 new cases of spinal cord injury (SCI) every year. There is yet a significant need for in vitro models… read more here.
Keywords: microfluidic platforms; neuronal injury; tbi sci; vitro ... See more keywords
3D stromal tissue equivalent affects intestinal epithelium morphogenesis in vitro
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DOI: 10.1002/bit.26522
Abstract: Current in vitro models of human intestine commonly fail to mimic the complex intestinal functions and features required for drug development and disease research. Here, we deeply investigate the interaction existing between epithelium and the… read more here.
Keywords: epithelium; tissue; vitro; epithelium morphogenesis ... See more keywords
Advances in periodontal stem cells and the regulating niche: From in vitro to in vivo
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DOI: 10.1002/dvg.23494
Abstract: Periodontium possesses stem cell populations for its self‐maintenance and regeneration, and has been proved to be an optimal stem cell source for tissue engineering. In vitro studies have shown that stem cells can be isolated… read more here.
Keywords: vitro; regulating niche; periodontal stem; stem ... See more keywords
Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing
Sign Up to like & getrecommendations! Published in 2021 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22444
Abstract: The organotypic human air‐liquid‐interface (ALI) airway tissue model has been used as an in vitro cell culture system for evaluating the toxicity of inhaled substances. ALI airway cultures are highly differentiated, which has made it… read more here.
Keywords: dna damage; airway cultures; toxicity; duplex sequencing ... See more keywords