Articles with "vitro activity" as a keyword



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The underappreciated in vitro activity of tedizolid against Bacteroides fragilis species, including strains resistant to metronidazole and carbapenems.

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Published in 2017 at "Anaerobe"

DOI: 10.1016/j.anaerobe.2016.09.008

Abstract: Because Bacteroides fragilis has the ability to develop mechanisms of resistance to almost all antibiotics, we studied the comparative in vitro activity of tedizolid against 124 Bacteroides group species clinical isolates, including carbapenem, metronidazole and piperacillin-tazobactam… read more here.

Keywords: activity tedizolid; underappreciated vitro; group species; vitro activity ... See more keywords
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[In-vitro activity of azithromycin in faecal isolates of Aeromonas hydrophila].

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Published in 2017 at "Anales de pediatria"

DOI: 10.1016/j.anpedi.2016.06.013

Abstract: Aeromonas es un bacilo Gram-negativo que presenta semejanza morfológica con las Enterobacterias. Se han descrito numerosas especies, siendo A. caviae, A. veronii y, fundamentalmente, A. hydrophila las más frecuentes. Estas bacterias se transmiten a través… read more here.

Keywords: azithromycin faecal; pacientes con; faecal isolates; con ... See more keywords
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In vitro activity of EDTA and TOL-463 against Neisseria gonorrhoeae.

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Published in 2019 at "Diagnostic microbiology and infectious disease"

DOI: 10.1016/j.diagmicrobio.2018.10.021

Abstract: Neisseria gonorrhoeae quickly develops drug resistance. Time-kill curves revealed that EDTA and TOL-463 inhibit growth similar to penicillin, ciprofloxacin, and azithromycin. Furthermore, synergistic and additive antimicrobial interactions occurred when EDTA and TOL-463 were combined with… read more here.

Keywords: edta tol; tol 463; vitro activity; neisseria gonorrhoeae ... See more keywords
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In Vitro Activity of Cefiderocol, a Novel Siderophore Cephalosporin, against Gram-Negative Bacilli Isolated from Patients in Canadian Intensive Care Units.

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Published in 2020 at "Diagnostic microbiology and infectious disease"

DOI: 10.1016/j.diagmicrobio.2020.115012

Abstract: The in vitro activity of cefiderocol was evaluated against Gram-negative bacilli isolated from patients in Canadian intensive care units from 2015 to 2017 using the Clinical and Laboratory Standards Institute (CLSI) broth microdilution method and… read more here.

Keywords: negative bacilli; gram negative; vitro activity; activity cefiderocol ... See more keywords
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Evaluation of the in vitro activity of WCK 5222 (cefepime/zidebactam) and currently available combination therapies against single- and double-carbapenemase producing Enterobacteriaceae: Expanding the zone of hope.

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Published in 2019 at "International journal of antimicrobial agents"

DOI: 10.1016/j.ijantimicag.2019.105863

Abstract: Cefepime/zidebactam (WCK 5222), a β-lactam/β-lactam enhancer antibiotic under development, was designed to retain in vitro activity against Enterobacteriaceae that simultaneously produce metallo-β-lactamase (MBL) and serine-β-lactamase (SBL). Currently, aztreonam (ATM) plus ceftazidime/avibactam (CZA) or meropenem/vaborbactam (M/V)… read more here.

Keywords: cefepime; vitro activity; cza atm; wck 5222 ... See more keywords
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Potent inhibitory activity of Taniborbactam towards NDM-1 and NDM-1Q119X mutants, and "in vitro" activity of cefepime/taniborbactam against MBLsproducing Enterobacterales.

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Published in 2020 at "International journal of antimicrobial agents"

DOI: 10.1016/j.ijantimicag.2020.106228

Abstract: The main goal of the present study was to investigate the "in vitro" activity of taniborbactam (VNRX-5133), a novel broad-spectrum bicyclic boronate, against NDM-1 and Q119E, Q119K, Q119C, Q119F, Q119V and Q119Y NDM-1 variants which… read more here.

Keywords: taniborbactam; vitro activity; activity taniborbactam; activity cefepime ... See more keywords
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In vivo and in vitro activity of a bis-arylidenecyclo-alkanone against fluconazole-susceptible and -resistant isolates of Candida albicans.

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Published in 2018 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2018.04.012

Abstract: OBJECTIVES Candida albicans is a commensal organism and opportunistic pathogen associated both with superficial (mucosal and cutaneous) and systemic infections. Extensive use of antifungal agents has led to reduced susceptibility to the few existing drugs,… read more here.

Keywords: activity bis; vitro activity; pmc; candida albicans ... See more keywords
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In vitro activity of dihydrofolate reductase inhibitors and other antibiotics against Gram-positive pathogens collected globally between 2004 and 2016.

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Published in 2019 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2018.10.018

Abstract: OBJECTIVES The objective of this study was to determine the in vitro activity of iclaprim and comparator agents against 7618 Gram-positive clinical isolates collected in the periods 2004-2006, 2012-2014 and 2015-2016. METHODS Antimicrobial susceptibility testing… read more here.

Keywords: globally 2004; gram positive; vitro activity; 2004 2016 ... See more keywords
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IN VITRO ACTIVITY OF CEFTAZIDIME-AVIBACTAM AGAINST GRAM-NEGATIVE STRAINS IN COLOMBIA 2014-2018.

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Published in 2022 at "Journal of global antimicrobial resistance"

DOI: 10.1016/j.jgar.2022.02.018

Abstract: BACKGROUND Ceftazidime/avibactam (CAZ/AVI) has shown in vitro activity against multidrug-resistant (MDR) Gram-negative bacteria, especially Enterobacterales and carbapenem-resistant Pseudomonas aeruginosa. However, in vitro activity of CAZ/AVI against Gram-negative bacteria in Colombian hospitals is still unknown. The… read more here.

Keywords: gram negative; vitro activity; caz avi; activity ... See more keywords
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[In vitro activity of delafloxacin against bacterial isolates from osteoarticular and skin infections in Buenos Aires, Argentina].

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Published in 2021 at "Revista Argentina de microbiologia"

DOI: 10.1016/j.ram.2021.02.012

Abstract: In vitro activities of delafloxacin, ciprofloxacin and levofloxacin were evaluated by epsilometric and disk diffusion methods against 181 bacterial isolates recovered from bone and skin infections. Isolates included were 84 Staphylococcus aureus (40 MRSA and… read more here.

Keywords: delafloxacin ciprofloxacin; vitro activity; cns; bacterial isolates ... See more keywords
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In vitro activity of newer β-lactam/β-lactamase inhibitor combinations, cefiderocol, plazomicin and comparators against carbapenemase-producing Klebsiella pneumoniae isolates.

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Published in 2023 at "Journal of chemotherapy"

DOI: 10.1080/1120009x.2023.2170906

Abstract: Infections by carbapenem-resistant Klebsiella pneumoniae (CRKP) remain one of the greatest healthcare threats associated with significant morbidity and mortality. New antimicrobials were recently developed to address this threat. We assessed the epidemiology of carbapenemase-producing K.… read more here.

Keywords: vitro activity; pneumoniae; klebsiella pneumoniae; activity ... See more keywords