Synthesis, in vitro antifungal evaluation and docking studies of novel derivatives of imidazoles and benzimidazoles
Sign Up to like & getrecommendations! Published in 2019 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-019-02369-7
Abstract: A series of imidazole and benzimidazole derivatives was designed and prepared in good yields via convenient and efficient two steps synthetic route using readily available starting materials. The structures of the synthesized compounds and their… read more here.
Keywords: evaluation docking; studies novel; docking studies; vitro antifungal ... See more keywords
In vitro antifungal activity of a novel topical triazole PC945 against emerging yeast Candida auris
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Antimicrobial Chemotherapy"
DOI: 10.1093/jac/dkz280
Abstract: Abstract Objectives Management of Candida auris infection is difficult as this yeast exhibits resistance to different classes of antifungals, necessitating the development of new antifungals. The aim of this study was to investigate the susceptibility… read more here.
Keywords: triazole pc945; vitro antifungal; voriconazole posaconazole; pc945 ... See more keywords
In Vitro Antifungal Effect of Acrylic Corneal Glue (N-Butyl-2-Cyanoacrylate).
Sign Up to like & getrecommendations! Published in 2019 at "Cornea"
DOI: 10.1097/ico.0000000000002061
Abstract: PURPOSE The purpose of this study was to evaluate the in vitro antifungal effects of n-butyl-2-cyanoacrylate (nB2CA; Histoacryl Blue; B. Braun, Melsungen, Germany) against a variety of different fungal species. METHODS Inocula taken from suspensions… read more here.
Keywords: vitro antifungal; spp; butyl cyanoacrylate; zone inhibition ... See more keywords
In vitro antifungal susceptibility profile of Iranian Fusarium isolates: Emphasising on the potent inhibitory effect of efinaconazole compared to other drugs
Sign Up to like & getrecommendations! Published in 2022 at "Mycoses"
DOI: 10.1111/myc.13550
Abstract: Fusarium species are opportunistic human pathogens that remarkably cause fungal infections ranging from superficial to fatal invasive disseminated infections. Fusarium species are notoriously resistant to the majority of antifungal agents. read more here.
Keywords: antifungal susceptibility; vitro antifungal; iranian fusarium; profile iranian ... See more keywords
Low In Vitro Antifungal Activity of Tavaborole against Yeasts and Molds from Onychomycosis
Sign Up to like & getrecommendations! Published in 2018 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01632-18
Abstract: The in vitro activity of tavaborole, an FDA-approved antifungal drug, was compared to that of four antifungal agents against 170 clinical fungal isolates originating from patients with onychomycosis. Tavaborole had low activity against all isolates… read more here.
Keywords: treatment onychomycosis; activity tavaborole; vitro antifungal; low vitro ... See more keywords
In Vitro Antifungal Susceptibility of Candida Species Isolated from Iranian Patients with Denture Stomatitis
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/3086586
Abstract: Background Candida-associated denture stomatitis (CADS) is a common fungal infection in people who wear dentures. The main objective of this study was to make molecular identification of causative agents of CADS and in vitro antifungal… read more here.
Keywords: candida; vitro antifungal; iranian patients; denture stomatitis ... See more keywords
Biocompatible phospholipid-based mixed micelles for posaconazole ocular delivery: Development, characterization, and in - vitro antifungal activity
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomaterials Applications"
DOI: 10.1177/08853282221141962
Abstract: Current study intended to prepare and evaluate phospholipid-based, mixed micelles (MMs) to improve the ocular delivery of posaconazole (POS), a broad-spectrum antifungal drug. For this, MMs based on egg phosphatidylcholine (EPC), as the main component,… read more here.
Keywords: ocular delivery; antifungal activity; vitro antifungal; phospholipid based ... See more keywords
In vitro Antifungal Activity of Olive (Olea europaea) Leaf Extracts Loaded in Chitosan Nanoparticles
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2020.00151
Abstract: Olive leaf extract is characterized by a high content of phenols and flavonoids (oleuropein, luteolin, and their derivatives). These compounds are defined as secondary metabolites and exert such as anti-inflammatory, antioxidant, and antimicrobial activities. We… read more here.
Keywords: olive leaf; vitro antifungal; leaf; antifungal activity ... See more keywords
In Vitro Antifungal Drug Resistance Profiles of Clinically Relevant Members of the Mucorales (Mucoromycota) Especially with the Newer Triazoles
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Fungi"
DOI: 10.3390/jof7040271
Abstract: Mucoromycoses (infections caused by members of the order Mucorales, phylum Mucoromycota [ex-Zygomycota]) are highly destructive, rapidly progressive infections, with dire prognoses especially when they occur in immunocompromised hosts. Current treatment guidelines recommend liposomal formulations of… read more here.
Keywords: drug resistance; vitro antifungal; newer triazoles; antifungal drug ... See more keywords
In Vitro Antifungal Susceptibility Profile of Miltefosine against a Collection of Azole and Echinocandins Resistant Fusarium Strains
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8070709
Abstract: Fusarium species are filamentous fungi that cause a variety of infections in humans. Because they are commonly resistant to many antifungal drugs currently available in clinical settings, research into alternative targets in fungal cells and… read more here.
Keywords: antifungal susceptibility; vitro antifungal; susceptibility profile; fusarium ... See more keywords
In Vitro Antifungal Activity of LL-37 Analogue Peptides against Candida spp.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8111173
Abstract: Fungal infections have increased in recent decades with considerable morbidity and mortality, mainly in immunosuppressed or admitted-to-the-ICU patients. The fungal resistance to conventional antifungal treatments has become a public health problem, especially with Candida that… read more here.
Keywords: antifungal activity; candida spp; activity analogue; vitro antifungal ... See more keywords