Synthesis and in vitro antileishmanial efficacy of novel benzothiadiazine‐1,1‐dioxide derivatives
Sign Up to like & getrecommendations! Published in 2021 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202000280
Abstract: Leishmaniasis is a major vector‐borne parasitic disease that affects thousands of people in tropical and subtropical developing countries. In 2019 alone, it killed 26,000–65,000 individuals. Leishmaniasis is curable, yet its eradication and elimination are hampered… read more here.
Keywords: vitro antileishmanial; antileishmanial efficacy; efficacy novel; synthesis vitro ... See more keywords
Synthesis, in vitro Antileishmanial Efficacy and Hit/Lead Identification of Nitrofurantoin‐Triazole Hybrids
Sign Up to like & getrecommendations! Published in 2022 at "Chemmedchem"
DOI: 10.1002/cmdc.202200023
Abstract: Leishmaniasis is a vector‐borne neglected parasitic infection affecting thousands of individuals, mostly among populations in low‐ to moderate‐income developing countries. In the absence of protective vaccines, the management of the disease banks solely on chemotherapy.… read more here.
Keywords: nitrofurantoin triazole; synthesis vitro; efficacy hit; vitro antileishmanial ... See more keywords
Synthesis and in vitro antileishmanial efficacy of benzyl analogues of nifuroxazide
Sign Up to like & getrecommendations! Published in 2020 at "Drug Development Research"
DOI: 10.1002/ddr.21755
Abstract: Leishmaniasis is a vector‐borne parasitic disease that mostly affects populations in tropical and subtropical countries. There is currently no vaccine to protect against and only a handful of drugs are available to treat this disease.… read more here.
Keywords: vitro antileishmanial; synthesis vitro; benzyl analogues; antileishmanial efficacy ... See more keywords
Synthesis and in vitro antileishmanial activity of alkylene-linked nitrofurantoin-triazole hybrids.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of medicinal chemistry"
DOI: 10.2139/ssrn.4261625
Abstract: Leishmaniasis is a vector-borne parasitic disease that mostly affects populations in tropical and sub-tropical countries. There is currently no protective anti-leishmanial vaccine and only a paucity of clinical drugs is available to treat this disease… read more here.
Keywords: activity alkylene; synthesis vitro; alkylene; vitro antileishmanial ... See more keywords
In Vitro Antileishmanial Activity of Achillea santolina Essential Oil against Leishmania infantum Promastigote by Methylthiazole Tetrazolium (MTT) and Trypan Blue Colorimetric Methods.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Razi Institute"
DOI: 10.22092/ari.2020.352245.1555
Abstract: Leishmaniasis causes parasitic infections, especially in developing countries. The disease has not yet been controlled because of the absence of an effective vaccine and low-cost treatment. Achillea santolina essential oil (ASEO) might control the disease… read more here.
Keywords: antileishmanial activity; vitro antileishmanial; mtt trypan; trypan blue ... See more keywords