Articles with "vitro antimalarial" as a keyword



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N-Substituted aminoquinoline-pyrimidine hybrids: Synthesis, in vitro antimalarial activity evaluation and docking studies.

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Published in 2019 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2018.11.021

Abstract: A series of novel molecular hybrids based on 4-aminoquinoline-pyrimidine were synthesized and examined for their antimalarial activity. Most of the compounds were found to have potent in vitro antimalarial activity against both CQ-sensitive D6 and CQ-resistant… read more here.

Keywords: vitro antimalarial; docking studies; aminoquinoline pyrimidine; antimalarial activity ... See more keywords