Synthesis and in vitro antimycobacterial and antileishmanial activities of hydroquinone-triazole hybrids
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DOI: 10.1007/s00044-020-02553-0
Abstract: Infectious diseases such as tuberculosis and leishmaniasis are leading causes of human death. One of the major factors contributing to the poor control of these diseases is primarily the reduced effectiveness of the existing chemotherapies… read more here.
Keywords: vitro antimycobacterial; triazole hybrids; hydroquinone triazole; chemistry ... See more keywords
In vitro antimycobacterial studies of flavonols from Bauhinia vahlii Wight and Arn
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DOI: 10.1007/s13205-021-02672-4
Abstract: Mycobacterial infections and fast-growing strains are increasing globally with 8 million new cases and 1.8 million fatalities per annum worldwide. The acid-fast bacterium, Mycobacterium tuberculosis (M.t), can spread diseases like tuberculosis (Tb) and weaken the… read more here.
Keywords: vitro antimycobacterial; vahlii; vahlii wight; tuberculosis ... See more keywords
Synthesis, In silico Molecular Docking and Pharmacokinetic Studies, In vitro Antimycobacterial and Antimicrobial Studies of New Imidozolones Clubbed with Thiazolidinedione.
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DOI: 10.2174/1573409914666180516113552
Abstract: BACKGROUND A series of (E)-5-(4-((Z)-4-substitutedbenzylidene-2-thienylmethylene-5-oxo- 2-phenyl-4,5-dihydro-1H-imidazol-1-yl) benzylidene)thiazolidine-2,4-diones were synthesized and evaluated for antimycobacterial and antimicrobial activity. All these ligands were docked against protein (InhA) Enoyl-ACP reductase of the type II fatty acid syntase (FAS-II) system,… read more here.
Keywords: vitro antimycobacterial; silico molecular; antimycobacterial antimicrobial; activity ... See more keywords