Synthesis, in vitro antiproliferative activity, antioxidant activity and molecular modeling studies of new carbazole Mannich bases
Sign Up to like & getrecommendations! Published in 2017 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-017-1927-5
Abstract: A new class of carbazole Mannich bases were synthesized from 4-hydroxycarbazole by reacting with aromatic aldehydes and cyclic amines under mild reaction conditions in good yields. The method does not require column chromatographic purification for… read more here.
Keywords: carbazole mannich; mannich bases; vitro antiproliferative; antiproliferative activity ... See more keywords
In vitro antiproliferative study of novel adamantyl pyridin-4-ones
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Diversity"
DOI: 10.1007/s11030-017-9763-6
Abstract: The preparation of several N-aryl-substituted (phenyl, p-methylphenyl, p-methoxyphenyl, p-nitrophenyl, p-aminophenyl, p-hydroxyphenyl) 3-hydroxy-2-methylpyridin-4-ones as well as their adamantyl derivatives is described, and their in vitro antitumor properties were investigated. The compounds were synthesized in good yields… read more here.
Keywords: study novel; novel adamantyl; study; antiproliferative study ... See more keywords
Comparative Study on the Chemical Structure and In Vitro Antiproliferative Activity of Anthocyanins in Purple Root Tubers and Leaves of Sweet Potato ( Ipomoea batatas).
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.8b05473
Abstract: The structure and in vitro antiproliferative activity of anthocyanins in the root tubers of a sweet potato variety cv. Bhu Krishna and the purple leaves of a promising accession S-1467 were studied with the objectives… read more here.
Keywords: root tubers; vitro antiproliferative; structure vitro; antiproliferative activity ... See more keywords
In vitro antiproliferative activity of alkaloids isolated from Tabernaemontana catharinensis A.DC (Apocynaceae).
Sign Up to like & getrecommendations! Published in 2022 at "Natural product research"
DOI: 10.1080/14786419.2021.2017928
Abstract: In this work, four alkaloids from the stem bark of T. catharinensis were isolated, namely: voacangine (1); ethyl apovincaminate (2); affinisine (3) and voachalotine (4). The alkaloids were tested in vitro for antiproliferative capacity in… read more here.
Keywords: vitro antiproliferative; activity alkaloids; catharinensis; antiproliferative activity ... See more keywords
Investigation of TNBC in vitro Antiproliferative Effects of Versatile Pirrolo[1,2-a]quinoxaline Compounds
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2019.00012
Abstract: The triple-negative breast cancer (TNBC) is characterized by a more aggressive nature and poorer prognosis, nowadays none pharmaceutical approach is still available. For this reason, the research of new active compounds and attractive targets represents… read more here.
Keywords: vitro antiproliferative; versatile pirrolo; effects versatile; tnbc vitro ... See more keywords
Green Synthesis of Silver Nanoparticles Using Populi gemmae Extract: Preparation, Physicochemical Characterization, Antimicrobial Potential and In Vitro Antiproliferative Assessment
Sign Up to like & getrecommendations! Published in 2022 at "Materials"
DOI: 10.3390/ma15145006
Abstract: Green route is an economic, facile and eco-friendly method, employed for the synthesis of various types of nanoparticles, having it as a starting point biological entity, especially as a plant extract. The present study aims… read more here.
Keywords: populi gemmae; synthesis; vitro antiproliferative; silver nanoparticles ... See more keywords
In Vitro Antiproliferative Evaluation of Synthetic Meroterpenes Inspired by Marine Natural Products
Sign Up to like & getrecommendations! Published in 2019 at "Marine Drugs"
DOI: 10.3390/md17120684
Abstract: Several marine natural linear prenylquinones/hydroquinones have been identified as anticancer and antimutagenic agents. Structure-activity relationship studies on natural compounds and their synthetic analogs demonstrated that these effects depend on the length of the prenyl side… read more here.
Keywords: synthetic meroterpenes; marine natural; vitro antiproliferative; inspired marine ... See more keywords