Relevance of desorption kinetics and permeability for in vitro-based predictions of hepatic clearance in fish.
Sign Up to like & getrecommendations! Published in 2021 at "Aquatic toxicology"
DOI: 10.1016/j.aquatox.2021.105825
Abstract: The impact of desorption kinetics and permeation kinetics on in vitro-based predictions of in vivo hepatic blood clearances is investigated in the present study. Most commonly, possible limitations due to slow desorption of chemicals from… read more here.
Keywords: vitro based; based predictions; permeability; clearance ... See more keywords
Approach toward In Vitro-Based Human Toxicity Effect Factors for the Life Cycle Impact Assessment of Inhaled Low-Solubility Particles
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Science & Technology"
DOI: 10.1021/acs.est.2c01816
Abstract: Today’s scarcity of animal toxicological data for nanomaterials could be lifted by substituting in vivo data with in vitro data to calculate nanomaterials’ effect factors (EF) for Life Cycle Assessment (LCA). Here, we present a… read more here.
Keywords: factors life; life cycle; vitro based; effect factors ... See more keywords