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Published in 2019 at "Biotechnology Journal"
DOI: 10.1002/biot.201800358
Abstract: Bone remodeling is strongly linked to external mechanical signals. Such stimuli are widely used in vitro for bone tissue engineering by applying mechanical solicitations to cell cultures so as to trigger specific cell responses. However,…
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Keywords:
vitro bone;
optimal protocol;
mechanical solicitations;
tissue ... See more keywords
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Published in 2021 at "Journal of biomaterials applications"
DOI: 10.1177/08853282211027889
Abstract: In this study, it was aimed to present an approach for the development of multi-layered tissue engineering constructs by using cell sheet engineering. Briefly, MC3T3-E1 mouse pre-osteoblast cells were cultured in temperature-responsive plates (Nunc Upcell®)…
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Keywords:
vitro bone;
bone model;
cell sheets;
multi layered ... See more keywords
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Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.915277
Abstract: To study human physiological and pathological bone remodeling while addressing the principle of replacement, reduction and refinement of animal experiments (3Rs), human in vitro bone remodeling models are being developed. Despite increasing safety-, scientific-, and…
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Keywords:
resorption;
human vitro;
hpl;
bone ... See more keywords