In vitro and clinical investigations to determine the drug-drug interaction potential of entrectinib, a small molecule inhibitor of neurotrophic tyrosine receptor kinase (NTRK)
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DOI: 10.1007/s10637-021-01156-9
Abstract: Background Entrectinib is a CNS-active, potent inhibitor of tyrosine receptor kinases A/B/C, ROS1 and anaplastic lymphoma kinase approved for use in patients with solid tumors. We describe the in vitro and clinical studies investigating potential… read more here.
Keywords: inhibitor; entrectinib; vitro clinical; drug ... See more keywords
In Vitro Simulation and In Vivo Assessment of Tooth Wear: A Meta-Analysis of In Vitro and Clinical Research
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DOI: 10.3390/ma12213575
Abstract: Tooth wear may be described as a side-effect of occlusal forces that may be further induced by the common use of contemporary prosthetic materials in practice. The purpose of this systematic review was to appraise… read more here.
Keywords: research; tooth wear; vitro clinical; study ... See more keywords