Chemotherapeutic dosing implicated by pharmacodynamic modeling of in vitro cytotoxic data: a case study of paclitaxel
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Pharmacokinetics and Pharmacodynamics"
DOI: 10.1007/s10928-017-9540-2
Abstract: Conventional maximum tolerated doses (MTD) in chemotherapy are recently challenged by an alternative dosing method with low doses and high dosing frequency (LDHF). Still, it remains unclear which chemotherapies would potentially benefit from LDHF. The… read more here.
Keywords: chemotherapeutic dosing; cytotoxic; model; cytotoxic data ... See more keywords
Characterization and in vitro cytotoxic assessment of zinc oxide nano-particles in human epidermoid carcinoma cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of environmental chemical engineering"
DOI: 10.1016/j.jece.2021.105636
Abstract: Abstract The study was designed to evaluate the effect of varying concentrations of ion-carriers on the synthesis of zinc oxide nano-particles (ZONs). We also evaluated the anti-proliferative activity, morphological changes, ROS generation, nuclear apoptosis and… read more here.
Keywords: nano particles; oxide nano; vitro cytotoxic; characterization vitro ... See more keywords
Ripening of ‘Hass’ avocado mesocarp alters its phytochemical profile and the in vitro cytotoxic activity of its methanolic extracts
Sign Up to like & getrecommendations! Published in 2020 at "South African Journal of Botany"
DOI: 10.1016/j.sajb.2019.09.020
Abstract: Abstract Avocado is an excellent source of phytochemicals with remarkable bioactive properties. This study evaluated the effect of ripeness stage of ‘Hass’ avocado on the profile and content of lipophilic and hydrophilic phytochemicals and their… read more here.
Keywords: methanolic extracts; activity; vitro cytotoxic; hass avocado ... See more keywords
In vitro cytotoxic activity of Cuphea ingrata Cham. & Schltdl. extracts related to the oenothein B content
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DOI: 10.1080/14786419.2022.2103699
Abstract: Abstract Cuphea ingrata is a traditional medicinal plant species of the Lythraceae family. This work reports on the cytotoxic activity of the methanolic extract from the aerial parts of C. ingrata and the n-butanol and… read more here.
Keywords: vitro cytotoxic; cuphea ingrata; activity; cytotoxic activity ... See more keywords
Synthesis, Characterization, and Preliminary In Vitro Cytotoxic Evaluation of a Series of 2-Substituted Benzo [d] [1,3] Azoles
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DOI: 10.3390/molecules26092780
Abstract: A series of benzo [d] [1,3] azoles 2-substituted with benzyl- and allyl-sulfanyl groups were synthesized, and their cytotoxic activities were in vitro evaluated against a panel of six human cancer cell lines. The results showed… read more here.
Keywords: benzo azoles; series; vitro cytotoxic; characterization preliminary ... See more keywords
Improvement of the In Vitro Cytotoxic Effect on HT-29 Colon Cancer Cells by Combining 5-Fluorouacil and Fluphenazine with Green, Red or Brown Propolis
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28083393
Abstract: Cancer is regard as one of the key factors of mortality and morbidity in the world. Treatment is mainly based on chemotherapeutic drugs that, when used in targeted therapies, have serious side effects. 5-fluorouracil (5-FU)… read more here.
Keywords: brown propolis; combination; vitro cytotoxic; propolis ... See more keywords
In Silico Pharmacokinetic Profiling of the Identified Bioactive Metabolites of Pergularia tomentosa L. Latex Extract and In Vitro Cytotoxic Activity via the Induction of Caspase-Dependent Apoptosis with S-Phase Arrest
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15091132
Abstract: The in vitro cytotoxic efficacy of plant latex from Pergularia tomentosa L. was studied using five human cancer cell lines: HeLa cells (cervical carcinoma cells), A-549 (lung carcinoma), Panc-1 (pancreatic carcinoma cells), MDA-MB-231 (metastatic mammary… read more here.
Keywords: cell; pergularia tomentosa; latex; plant latex ... See more keywords
In Vitro Cytotoxic Potential of Selected Jordanian Flora and Their Associated Phytochemical Analysis
Sign Up to like & getrecommendations! Published in 2023 at "Plants"
DOI: 10.3390/plants12081626
Abstract: Traditional medicines are a significant source of phytochemicals with potential anticancer effects. Ten Jordanian plants were chosen to be tested for cytotoxicity on human colorectal (HT-29) and breast adenocarcinoma (MCF-7) cell lines. The ethanol extracts… read more here.
Keywords: clematis cirrhosa; vitro cytotoxic; potential selected; selected jordanian ... See more keywords
In-vitro Cytotoxic Activity of E. coli Outer Membrane Vesicles (OMVs) Against Breast Cancer (MCF-7) Cell Line
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DOI: 10.37506/mlu.v21i1.2355
Abstract: Twenty-five samples of urine were collected from patients suffering Urinary Tract Infection (UTI) fromhospital in Baghdad,twenty-two bacterial isolated (88%) were identified. From our result showed the E. colinumber 5 is the best bacterial virulence factor… read more here.
Keywords: cell line; activity coli; cytotoxic activity; cell ... See more keywords
In vitro cytotoxic activity of Verbascum alceoides against cervix carcinoma cells
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Reports in Pharmaceutical Sciences"
DOI: 10.4103/jrptps.jrptps_65_19
Abstract: Background: Verbascum species showed various pharmacological activities including anti-inflammatory, antitussive, antiulcerogenic, immunomodulatory, antimicrobial, antimalarial, antioxidant, and anticancer activities. Objectives: The aim of this work was to evaluate cytotoxicity of different fractions of Verbascum alceoides, which… read more here.
Keywords: verbascum; carcinoma; methanol; cytotoxic activity ... See more keywords