In Vitro Differentiated Human Stem Cell-Derived Neurons Reproduce Synaptic Synchronicity Arising during Neurodevelopment
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DOI: 10.1016/j.stemcr.2020.05.015
Abstract: Summary Neurons differentiated from induced pluripotent stem cells (iPSCs) typically show regular spiking and synaptic activity but lack more complex network activity critical for brain development, such as periodic depolarizations including simultaneous involvement of glutamatergic… read more here.
Keywords: stem cell; vitro differentiated; derived neurons; activity ... See more keywords