Generating Human iPSC-Derived Astrocytes with Chemically Defined Medium for In Vitro Disease Modeling.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9477-9_3
Abstract: To better understand and model neurological, in particular neurodegenerative diseases, human induced pluripotent stem cells (hiPSCs) offer a great source for generation of neural cells. We provide a protocol for the differentiation of hiPSc-derived astrocytes… read more here.
Keywords: vitro disease; derived astrocytes; generating human; human ipsc ... See more keywords
Biomimetic cardiovascular platforms for in vitro disease modeling and therapeutic validation.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2018.08.010
Abstract: Bioengineered tissues have become increasingly more sophisticated owing to recent advancements in the fields of biomaterials, microfabrication, microfluidics, genetic engineering, and stem cell and developmental biology. In the coming years, the ability to engineer artificial… read more here.
Keywords: vitro disease; validation; therapy validation; biomimetic cardiovascular ... See more keywords
Animal Disease Models and Patient-iPS-Cell-Derived In Vitro Disease Models for Cardiovascular Biology—How Close to Disease?
Sign Up to like & getrecommendations! Published in 2023 at "Biology"
DOI: 10.3390/biology12030468
Abstract: Simple Summary Currently, rodents and pigs are the primary disease models used in cardiovascular research. Generally, larger animals that are more closely related to humans are better-suited disease models. However, they can have restricted or… read more here.
Keywords: derived vitro; vitro disease; disease; disease models ... See more keywords