In Vitro Effect of Dovitinib (TKI258), a Multi-Target Angiokinase Inhibitor on Aggressive Meningioma Cells
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DOI: 10.1080/07357907.2020.1773844
Abstract: Abstract Background: Meningiomas represent ∼30% of primary central nervous system (CNS) tumors. Although advances in surgery and radiotherapy have significantly improved survival, there remains an important subset of patients whose tumors have more aggressive behavior… read more here.
Keywords: multi; dovitinib; inhibitor; vitro effect ... See more keywords
In vitro effect on the proteolytic activity of papain with proteins of the skin as substrate
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DOI: 10.1111/ics.12805
Abstract: This work aims to evaluate the effects of enzyme concentration, pH, temperature and time course degree of hydrolysis (DH) of papain regarding further development of pharmaceutical and cosmetic formulations. read more here.
Keywords: proteins skin; vitro effect; proteolytic activity; activity papain ... See more keywords
In Vitro Effect of Mitochondria-Targeted Triphenylphosphonium-Based Compounds (Honokiol, Lonidamine, and Atovaquone) on the Platelet Function and Cytotoxic Activity
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DOI: 10.3389/fphar.2022.893873
Abstract: Introduction: Obtaining triphenylphosphonium salts derived from anticancer compounds to inhibit mitochondrial metabolism is of major interest due to their pivotal role in reactive oxygen species (ROS) production, calcium homeostasis, apoptosis, and cell proliferation. However, the… read more here.
Keywords: function; effect; vitro effect; platelet ... See more keywords