In vitro evaluation of physicochemical variables on the nematophagous fungus Duddingtonia flagrans
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.202100039
Abstract: Duddingtonia flagrans is a biological alternative to the use of anthelmintic drugs in ruminants. This fungus must be ingested by the animal, pass through the cavities of the digestive tract and reach the feces where… read more here.
Keywords: physicochemical variables; evaluation physicochemical; duddingtonia; vitro evaluation ... See more keywords
In Vitro Evaluation of Antisense-Mediated Exon Inclusion for Spinal Muscular Atrophy.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8651-4_27
Abstract: Spinal muscular atrophy (SMA), the most common gentic cause of infantile death caused by mutations in the SMN1 gene, presents a unique case in the field of splice modulation therapy, where a gene (or lack… read more here.
Keywords: evaluation antisense; spinal muscular; vitro evaluation; muscular atrophy ... See more keywords
In vitro evaluation of the bioaccessibility of antioxidative properties in commercially baby foods
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Food Science and Technology"
DOI: 10.1007/s13197-020-04384-8
Abstract: Fruit-vegetable based products are essential for infants as they widely used the first complementary solid foods. This study aimed to investigate the physicochemical properties, the antioxidant capacities, total phenolic content, and bioaccessibility of 24 different… read more here.
Keywords: evaluation bioaccessibility; antioxidative properties; vitro evaluation; content ... See more keywords
In vivo and in vitro evaluation of pharmacological activities of Adenia trilobata (Roxb.)
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2020.100772
Abstract: Adenia trilobata, locally known as akandaphal in Bangladesh, has some traditional uses. Leaves and stems extracted with pure methanol (MEATL, MEATS) and fractioned by n-hexane (NFATL, NFATS), which was subjected to qualitative phytochemical analysis. The… read more here.
Keywords: vivo vitro; pharmacological activities; activities adenia; evaluation pharmacological ... See more keywords
Design, synthesis, in vitro Evaluation and docking studies on dihydropyrimidine-based urease inhibitors.
Sign Up to like & getrecommendations! Published in 2017 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2017.07.003
Abstract: In our previous report, we have identified 3,4-dihydropyrimidine scaffold as promising class of urease inhibitor in a structure based virtual screen (SBVS) experiment. In present study, we attempted to optimize the scaffold by varying C-5… read more here.
Keywords: design synthesis; evaluation docking; urease inhibitors; docking studies ... See more keywords
Identification, in vitro evaluation and modeling studies of the constituents from the roots of Arnebia euchroma for antitumor activity and STAT3 inhibition.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.103655
Abstract: Phytochemical investigation of the roots of Arnebia euchroma led to the isolation of a new dimeric naphthoquinone, shikometabolin H (1), a new meroterpeniod, epoxyarnebinol (5) and a new ring A-seco hopane triterpenoid, 2, 3-secodiplopterol dioic… read more here.
Keywords: identification vitro; vitro evaluation; stat3; arnebia euchroma ... See more keywords
Design, synthesis, and in vitro evaluation of novel triazole analogues featuring isoxazole moieties as antifungal agents.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.103982
Abstract: In order to develop novel antifungal agents, based on our previous work, a series of (2R,3R)-3-((3-substitutied-isoxazol-5-yl)methoxy)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl) butan-2-ol (a1-a26) were designed and synthesized. All of the compounds exhibited good in vitro antifungal activities against eight human… read more here.
Keywords: design synthesis; antifungal agents; evaluation novel; vitro evaluation ... See more keywords
Design, synthesis, and in vitro evaluation of 4-aminoalkyl-1(2H)-phthalazinones as potential multifunctional anti-Alzheimer's disease agents.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104895
Abstract: A series of 4-aminoalkyl-1(2H)-phthalazinone derivatives was designed and synthesized as potential multifunctional agents for Alzheimer's disease (AD) treatment. In vitro biological assay results demonstrated that most synthesized compounds exhibited significant AChE inhibition, moderate to high… read more here.
Keywords: design synthesis; alzheimer disease; potential multifunctional; vitro evaluation ... See more keywords
Co-substitutions of iron and manganese in zirconia. Synthesis, structural, magnetic, mechanical and in vitro evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Ceramics International"
DOI: 10.1016/j.ceramint.2019.09.016
Abstract: Abstract Co-substitution of iron and manganese in ZrO2 and the subsequent structural analysis, mechanical, magnetic and in vitro evaluation is presented. Five different compositions have been synthesized by varying the concentrations of iron and manganese… read more here.
Keywords: manganese zirconia; substitutions iron; vitro evaluation; iron manganese ... See more keywords
In vitro evaluation of antifungal combination against Cryptococcus neoformans.
Sign Up to like & getrecommendations! Published in 2019 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2018.12.003
Abstract: This study evaluated combinations of amphotericin B with anidulafungin, caspofungin, and micafungin against 30 clinical isolates of Cryptococcus neoformans following the CLSI M27-A3 and the checkerboard microdilution method. The combination amphotericin B + micafungin showed 60% of… read more here.
Keywords: combination; cryptococcus neoformans; vitro evaluation; antifungal combination ... See more keywords
The impact of gastrointestinal mucus on nanoparticle penetration – in vitro evaluation of mucus‐penetrating nanoparticles for photodynamic therapy
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2019.03.010
Abstract: Abstract Over the last years nanoparticles (NP) have become a promising vehicle as drug delivery systems for photodynamic therapy (PDT), combining the advantages of an effective drug transport to the target cells and the reduction… read more here.
Keywords: photodynamic therapy; vitro evaluation; mucus penetrating; drug ... See more keywords