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Published in 2017 at "Drug testing and analysis"
DOI: 10.1002/dta.2306
Abstract: With an increasing number of prohibited substances in doping controls, knowledge about their metabolism is crucial for efficient analysis. While for low molecular mass molecules, standard protocols for in vitro metabolism experiments are well established,…
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Keywords:
metabolites selected;
generated metabolites;
metabolism;
vitro generated ... See more keywords
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Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.5242
Abstract: Background Psoriatic arthritis (PsA) is a spondyloarthritis affecting the joint and skin. The genetic association with HLA Class I and the clinical efficacy of IL-17A inhibitors in the treatment of PsA suggest a potential role…
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Keywords:
cytokine;
cd8;
cd8 cells;
vitro generated ... See more keywords
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Published in 2020 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2019-000474
Abstract: Background Type 1 conventional dendritic cells (cDC1s) possess efficient antigen presentation and cross-presentation activity, as well as potent T cell priming ability. Tissue-resident cDC1s (CD103+ cDC1s in mice, CD141+ cDC1s in humans) are linked with…
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Keywords:
cd103 cdc1s;
vitro generated;
generated cd103;
cdc1s ... See more keywords
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Published in 2022 at "Journal of innate immunity"
DOI: 10.1159/000525088
Abstract: Immune reactions after trauma are characterized by immediate activation of innate immunity and simultaneously downregulation of adaptive immunity leading to a misbalanced immunohomeostasis and immunosuppression of the injured host. Therefore, the susceptibility to secondary infections…
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Keywords:
cell;
vitro generated;
myeloid derived;
suppressor cells ... See more keywords
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Published in 2018 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2018.02417
Abstract: Tuberculosis (TB) has tremendous public health relevance. It most frequently affects the lung and is characterized by the development of unique tissue lesions, termed granulomas. These lesions encompass various immune populations, with macrophages being most…
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Keywords:
human monocytic;
vitro generated;
tuberculosis;
generated granulomas ... See more keywords