Review: In vitro generation of red blood cells for transfusion medicine: Progress, prospects and challenges.
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology advances"
DOI: 10.1016/j.biotechadv.2018.09.006
Abstract: In vitro generation of red blood cells (RBCs) has the potential to circumvent the shortfalls in global demand for blood for transfusion applications. The conventional approach for RBC generation has been from differentiation of hematopoietic… read more here.
Keywords: medicine; red blood; generation red; generation ... See more keywords
A new approach to the role of IL‐7 and TGF‐ß in the in vitro generation of thymus‐derived CD4+CD25+Foxp3+ regulatory T cells
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2017.07.019
Abstract: HighlightsTGF‐&bgr; involvement in the induction of tTregs in vitro is shown.The important role of IL‐7 in thymic Treg generation is indicated.IL‐7 and TGF‐&bgr; create conditions for efficient tTreg in vitro generation.Generated in vitro tTregs maintain… read more here.
Keywords: generation; tgf; thymus derived; role ... See more keywords
In vitro generation of functional murine heart organoids via FGF4 and extracellular matrix
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-18031-5
Abstract: Our understanding of the spatiotemporal regulation of cardiogenesis is hindered by the difficulties in modeling this complex organ currently by in vitro models. Here we develop a method to generate heart organoids from mouse embryonic… read more here.
Keywords: generation functional; fgf4; heart organoids; heart ... See more keywords
In vitro generation of self-renewing human intestinal epithelia over planar and shaped collagen hydrogels
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DOI: 10.1038/s41596-020-00419-8
Abstract: The large intestine, with its array of crypts lining the epithelium and diverse luminal contents, regulates homeostasis throughout the body. In vitro crypts formed from primary human intestinal epithelial stem cells on a 3D shaped… read more here.
Keywords: collagen; self renewing; vitro generation; human intestinal ... See more keywords
In vitro Generation of Megakaryocytes and Platelets
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.713434
Abstract: Platelets, the tiny anucleate cells responsible for stopping bleeding through thrombosis, are derived from hematopoietic stem cells through a series of differentiation steps. Thrombocytopenia, characterized by abnormally low blood platelet counts, may arise from cancer… read more here.
Keywords: generation; blood; hematopoietic stem; vitro generation ... See more keywords
In Vitro Generation of Oocytes from Ovarian Stem Cells (OSCs): In Search of Major Evidence
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20246225
Abstract: The existence of ovarian stem cells (OSCs) in women as well as their physiological role in post-menopausal age are disputed. However, accumulating evidence demonstrated that, besides the animal models including primarily mice, even in adult… read more here.
Keywords: ovarian stem; cells oscs; evidence; vitro generation ... See more keywords