Generation of Bone Marrow-Derived Macrophages for In Vitro Infection Experiments.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9210-2_12
Abstract: Murine bone marrow-derived macrophages (BMMs) can be differentiated within 10 days from ex vivo bone marrow progenitor cells by supplementing the cell growth medium with colony stimulating factor-1 (CSF-1). Mature macrophages express specific myeloid markers… read more here.
Keywords: marrow derived; bone; derived macrophages; vitro infection ... See more keywords
Pre‐clinical in vitro infection models
Sign Up to like & getrecommendations! Published in 2017 at "Current Opinion in Pharmacology"
DOI: 10.1016/j.coph.2017.09.011
Abstract: HIGHLIGHTSIn vitro systems allow determination of dose and schedule for new drugs.Identifying this allows better patient outcomes and de‐risks drug development.The HFIM allows identification of dose and schedule for resistance suppression. &NA; Given the current… read more here.
Keywords: dose schedule; clinical vitro; pre clinical; vitro infection ... See more keywords
3D bioprinting of E. coli MG1655 biofilms on human lung epithelial cells for building complex in vitro infection models.
Sign Up to like & getrecommendations! Published in 2023 at "Biofabrication"
DOI: 10.1088/1758-5090/acd95e
Abstract: Biofilm-associated infections are causing over half a million deaths each year, raising the requirement for innovative therapeutic approaches. For developing novel therapeutics against bacterial biofilm infections, complex in vitro models that allow to study drug… read more here.
Keywords: vitro; infection models; vitro infection; coli mg1655 ... See more keywords