In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone
Sign Up to like & getrecommendations! Published in 2025 at "Drug Development Research"
DOI: 10.1002/ddr.70125
Abstract: Diabetes is a fast‐growing health issue in low‐ and middle‐income countries, with ~80% of diabetics living in the tropics and sub‐tropics. It is a deadly condition claiming the lives of millions of individuals annually, with… read more here.
Keywords: arylidene analogues; vitro leishmanicidal; efficacy; efficacy synthesized ... See more keywords
In Vitro Leishmanicidal Effect of Silibinin: Disrupting Redox Balance via Trypanothione Reductase Inhibition
Sign Up to like & getrecommendations! Published in 2025 at "ACS Omega"
DOI: 10.1021/acsomega.5c02606
Abstract: Visceral leishmaniasis, caused by the parasite Leishmania infantum, is a life-threatening disease with limited therapeutic options that are often associated with toxicity and resistance. In this study, we investigated the in vitro leishmanicidal effects of… read more here.
Keywords: disrupting redox; vitro leishmanicidal; trypanothione reductase; silibinin ... See more keywords
Synthesis and in vitro leishmanicidal activity of novel [1,2,3]triazolo[1,5-a]pyridine salts
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c7ra01070b
Abstract: Leishmaniasis remains a significant worldwide problem; it is of great interest to develop new drugs to fight this disease. Recently we described some [1,2,3]triazolo[1,5-a]pyridine compounds with significant leishmanicidal activity. The importance of water solubility in… read more here.
Keywords: vitro leishmanicidal; triazolo pyridine; novel triazolo; leishmanicidal activity ... See more keywords