Mechanistic insights into the reduced developmental capacity of in vitro matured oocytes and importance of cumulus cells in oocyte quality determination
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29786
Abstract: In vitro maturation of oocytes is a promising assisted reproductive technology (ART) for infertility treatment, although it is still not a routine technique for human ART due to reduced embryonic development. The aim of the… read more here.
Keywords: vitro matured; reduced developmental; matured oocytes; capacity vitro ... See more keywords
DNA methylation profile of single in vitro matured bovine oocytes
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23679
Abstract: Somatic cell nuclear transfer (SCNT) is commercially used despite incomplete nuclear reprogramming of the somatic cell nucleus by the enucleated oocyte compromising its efficiency. Oocyte selection is a key factor in increasing this efficiency as… read more here.
Keywords: vitro matured; single vitro; cell; dna methylation ... See more keywords
The Anti-oxidative Effects of Encapsulated Cysteamine During Mice In Vitro Matured Oocyte/Morula-Compact Stage Embryo Culture Model: a Comparison of High-Efficiency Nanocarriers for Hydrophilic Drug Delivery—a Pilot Study
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive Sciences"
DOI: 10.1007/s43032-020-00333-0
Abstract: Although it is well-recognized that antioxidant nano-encapsulation has many benefits such as minimizing side effects (e.g., high-dose toxicity), the most attention was paid to the hydrophobic antioxidant not hydrophilic. In this regard, we sought to… read more here.
Keywords: matured oocyte; cys; microscopy; vitro matured ... See more keywords
Impact of sperm DNA fragmentation on ICSI outcome and incidence of apoptosis of human pre-implantation embryos obtained from in vitro matured MII oocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.01.056
Abstract: BACKGROUND Sperm DNA integrity and oocyte quality significantly affect embryo development and survival. The current study evaluated embryo development and quality, as well as the expression level of apoptosis-related genes and microRNAs in embryo derived… read more here.
Keywords: embryos; apoptosis; vitro matured; sperm dna ... See more keywords
Tubulin posttranslational modifications in in vitro matured prepubertal and adult ovine oocytes.
Sign Up to like & getrecommendations! Published in 2018 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2018.04.007
Abstract: Microtubules (MTs), polymers of alpha/beta-tubulin heterodimers, are involved in crucial functions in eukaryotic cells. MTs physiology can be influenced by a variety of post-translational modifications (PTMs), including tyrosination, detyrosination, delta 2 modification, acetylation, polyglutamylation, polyglycylation.… read more here.
Keywords: meiotic spindle; adult; ovine oocytes; vitro matured ... See more keywords
Enhancing developmental potential of vitrified in vitro matured bovine oocytes using extracellular vesicles from large follicles
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-17981-4
Abstract: This study investigates the differential effects of extracellular vesicles (EVs) derived from bovine follicular fluid (FF) on bovine oocytes cryotolerance, focusing on EVs from small (3–5 mm) and large (> 9 mm) follicles, with the aim… read more here.
Keywords: extracellular vesicles; large follicles; vitrification; bovine oocytes ... See more keywords
Testosterone Supplementation Promotes Estrogen Synthesis of Buffalo Cumulus Cells Surrounding In Vitro-Matured Oocytes
Sign Up to like & getrecommendations! Published in 2024 at "Cellular Reprogramming"
DOI: 10.1089/cell.2023.0121
Abstract: Cumulus cells (CCs) synthesize estrogens that are essential for follicular development. However, the effects of androgen on estrogen production in buffalo CCs remain unknown. In the present study, the impacts of testosterone on estrogen synthesis… read more here.
Keywords: matured oocytes; buffalo; vitro matured; estrogen synthesis ... See more keywords
Transcriptional profiling reveals upregulation of p53 signaling in porcine embryos produced in vitro
Sign Up to like & getrecommendations! Published in 2025 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioaf113
Abstract: Abstract Although advances in the porcine embryo culture system have been achieved, the artificial environment continues to be stressful for the embryos, which hinders development. To identify areas of improvement, transcriptional profiling was performed on… read more here.
Keywords: matured cultured; culture; p53; vitro matured ... See more keywords
P–429 Calcium analysis and embryonic development of in vitro matured oocytes from transgender men
Sign Up to like & getrecommendations! Published in 2021 at "Human Reproduction"
DOI: 10.1093/humrep/deab130.428
Abstract: Can oocytes isolated from transgender men after oophorectomy support embryonic development? Embryo developmental arrest at 4–8cell stage (day 3 embryos) indicates poor quality of in vitro matured oocytes from transgender men. Gender affirming surgery for… read more here.
Keywords: vitro matured; embryonic development; matured oocytes; calcium ... See more keywords
P–547 Single-cell RNA sequencing identifies molecular regulations associated with poor maturation performance on rescue in vitro matured oocytes
Sign Up to like & getrecommendations! Published in 2021 at "Human Reproduction"
DOI: 10.1093/humrep/deab130.546
Abstract: What is the transcriptome signature associated with rescuein vitro matured (rIVM) oocytes? GATA–1/CREB1/WNT signaling axis was repressed in rIVM oocytes of poor quality. rIVM aims to produce mature oocytes (MII) for in vitro fertilization (IVF)… read more here.
Keywords: single cell; rivm; vitro matured; cell rna ... See more keywords
Improving vitrification efficiency of human in vitro matured oocytes by the addition of LEA proteins.
Sign Up to like & getrecommendations! Published in 2024 at "Human reproduction"
DOI: 10.1093/humrep/deae065
Abstract: STUDY QUESTION Can the addition of late embryogenesis-abundant (LEA) proteins as a cryoprotective agent during the vitrification cryopreservation of in vitro matured oocytes enhance their developmental potential after fertilization? SUMMARY ANSWER LEA proteins improve the… read more here.
Keywords: vitrification; matured oocytes; lea; group ... See more keywords