Mechanistic insights into the reduced developmental capacity of in vitro matured oocytes and importance of cumulus cells in oocyte quality determination
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29786
Abstract: In vitro maturation of oocytes is a promising assisted reproductive technology (ART) for infertility treatment, although it is still not a routine technique for human ART due to reduced embryonic development. The aim of the… read more here.
Keywords: vitro matured; reduced developmental; matured oocytes; capacity vitro ... See more keywords
DNA methylation profile of single in vitro matured bovine oocytes
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23679
Abstract: Somatic cell nuclear transfer (SCNT) is commercially used despite incomplete nuclear reprogramming of the somatic cell nucleus by the enucleated oocyte compromising its efficiency. Oocyte selection is a key factor in increasing this efficiency as… read more here.
Keywords: vitro matured; single vitro; cell; dna methylation ... See more keywords
The Anti-oxidative Effects of Encapsulated Cysteamine During Mice In Vitro Matured Oocyte/Morula-Compact Stage Embryo Culture Model: a Comparison of High-Efficiency Nanocarriers for Hydrophilic Drug Delivery—a Pilot Study
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive Sciences"
DOI: 10.1007/s43032-020-00333-0
Abstract: Although it is well-recognized that antioxidant nano-encapsulation has many benefits such as minimizing side effects (e.g., high-dose toxicity), the most attention was paid to the hydrophobic antioxidant not hydrophilic. In this regard, we sought to… read more here.
Keywords: matured oocyte; cys; microscopy; vitro matured ... See more keywords
Impact of sperm DNA fragmentation on ICSI outcome and incidence of apoptosis of human pre-implantation embryos obtained from in vitro matured MII oocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.01.056
Abstract: BACKGROUND Sperm DNA integrity and oocyte quality significantly affect embryo development and survival. The current study evaluated embryo development and quality, as well as the expression level of apoptosis-related genes and microRNAs in embryo derived… read more here.
Keywords: embryos; apoptosis; vitro matured; sperm dna ... See more keywords
Tubulin posttranslational modifications in in vitro matured prepubertal and adult ovine oocytes.
Sign Up to like & getrecommendations! Published in 2018 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2018.04.007
Abstract: Microtubules (MTs), polymers of alpha/beta-tubulin heterodimers, are involved in crucial functions in eukaryotic cells. MTs physiology can be influenced by a variety of post-translational modifications (PTMs), including tyrosination, detyrosination, delta 2 modification, acetylation, polyglutamylation, polyglycylation.… read more here.
Keywords: meiotic spindle; adult; ovine oocytes; vitro matured ... See more keywords
P–429 Calcium analysis and embryonic development of in vitro matured oocytes from transgender men
Sign Up to like & getrecommendations! Published in 2021 at "Human Reproduction"
DOI: 10.1093/humrep/deab130.428
Abstract: Can oocytes isolated from transgender men after oophorectomy support embryonic development? Embryo developmental arrest at 4–8cell stage (day 3 embryos) indicates poor quality of in vitro matured oocytes from transgender men. Gender affirming surgery for… read more here.
Keywords: vitro matured; embryonic development; matured oocytes; calcium ... See more keywords
P–547 Single-cell RNA sequencing identifies molecular regulations associated with poor maturation performance on rescue in vitro matured oocytes
Sign Up to like & getrecommendations! Published in 2021 at "Human Reproduction"
DOI: 10.1093/humrep/deab130.546
Abstract: What is the transcriptome signature associated with rescuein vitro matured (rIVM) oocytes? GATA–1/CREB1/WNT signaling axis was repressed in rIVM oocytes of poor quality. rIVM aims to produce mature oocytes (MII) for in vitro fertilization (IVF)… read more here.
Keywords: single cell; rivm; vitro matured; cell rna ... See more keywords
Advanced mare age impairs the ability of in vitro‐matured oocytes to correctly align chromosomes on the metaphase plate
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DOI: 10.1111/evj.12995
Abstract: Summary Background Advanced mare age is associated with declining fertility and an increased risk of early pregnancy loss. Compromised oocyte quality is probably the primary reason for reduced fertility, but the defects predisposing to embryonic… read more here.
Keywords: advanced mare; age; vitro matured; mare age ... See more keywords
Developmental competence of in vitro matured ovine oocytes vitrified in solutions with different concentrations of trehalose
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DOI: 10.1111/rda.13221
Abstract: This study aimed to determine the optimum concentration of trehalose in solutions used for vitrification of in vitro matured (IVM) ovine oocytes. IVM oocytes were randomly divided into four experimental (vitrified) and one control (fresh)… read more here.
Keywords: different concentrations; ovine oocytes; vitro matured; oocytes vitrified ... See more keywords
Dynamics of epigenetic remodeling in interspecies porcine zygotes
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DOI: 10.17221/5135-cjas
Abstract: The process of active paternal chromatin demethylation after fertilization in the pig is not fully understood and very inconsistent data have been published by different research groups. We have applied the interspecies intracytoplasmic sperm injection… read more here.
Keywords: produced vitro; dynamics epigenetic; vitro matured; zygotes produced ... See more keywords
Vitrification of In vitro-matured Oocytes: Effects of meiotic spindle morphology on clinical outcome
Sign Up to like & getrecommendations! Published in 2020 at "Reproductive and Developmental Medicine"
DOI: 10.4103/2096-2924.281854
Abstract: Objective: The meiotic spindle controls chromosome movement and mediates various functions essential for fertilization and early postfertilization events. This study aimed to examine whether vitrification causes meiotic damage in vitro- matured metaphase II (MII) human… read more here.
Keywords: vitrification; spindle morphology; meiotic spindle; vitro matured ... See more keywords