Identification of human in vitro metabolites of the haemoglobin S polymerization inhibitor voxelotor for doping control purposes.
Sign Up to like & getrecommendations! Published in 2023 at "Drug testing and analysis"
DOI: 10.1002/dta.3489
Abstract: Voxelotor (GBT440) is a haemoglobin S polymerization inhibitor used to treat anaemia in sickle cell disease. Due to an increase of arterial oxygen saturation as well as serum erythropoietin and haemoglobin, the World Anti-Doping Agency… read more here.
Keywords: vitro metabolites; haemoglobin polymerization; doping control; polymerization inhibitor ... See more keywords
Identification of In Vitro Metabolites of Synthetic Phenolic Antioxidants BHT, BHA, and TBHQ by LC-HRMS/MS
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DOI: 10.3390/ijms21249525
Abstract: Butylated hydroxytoluene (BHT) and its analogs, butylated hydroxyanisole (BHA) and tert-butyl-hydroquinone (TBHQ), are widely used synthetic preservatives to inhibit lipid oxidation in the food, cosmetic and pharmaceutical industries. Despite their widespread use, little is known… read more here.
Keywords: synthetic phenolic; metabolites synthetic; identification vitro; tbhq ... See more keywords