Effect of atorvastatin on lipoxygenase pathway‐related gene expression in an in vitro model of lipid accumulation in hepatocytes
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DOI: 10.1002/2211-5463.13552
Abstract: Lipid accumulation in hepatocytes can result from an imbalance between lipid acquisition and lipid catabolism. In recent years, it has been discovered that eicosanoids derived from arachidonic acid (AA) have the potential to create specialized… read more here.
Keywords: vitro model; lipoxygenase pathway; lipid accumulation; expression ... See more keywords
Engineered Microsystems for Spheroid and Organoid Studies.
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DOI: 10.1002/adhm.202001284
Abstract: 3D in vitro model systems such as spheroids and organoids provide an opportunity to extend the physiological understanding using recapitulated tissues that mimic physiological characteristics of in vivo microenvironments. Unlike 2D systems, 3D in vitro… read more here.
Keywords: microengineering techniques; vitro model; model systems; microsystems spheroid ... See more keywords
Neuroimmunomodulatory properties of DPSCs in an in vitro model of Parkinson's disease
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DOI: 10.1002/iub.1655
Abstract: In neurodegenerative diseases, such as Alzheimer's and Parkinson's, microglial cell activation is thought to contribute to their degeneration by producing neurotoxic compounds. While dental pulp stem cells (DPSCs) have been regarded as the next possible… read more here.
Keywords: properties dpscs; vitro model; parkinson; neuroimmunomodulatory properties ... See more keywords
Bowman‐Birk inhibitor modifies transcription of autophagy and apoptosis genes in an in vitro model of Alzheimer's disorder
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DOI: 10.1002/jcb.28391
Abstract: Alzheimer, a current neurodegenerative disorder has adverse effects on memory and behavior. β‐Amyloid peptide accumulations are the hallmarks of Alzheimer. Dysfunction of autophagy and apoptosis is detected in Alzheimer's disease. The effect of Bowman‐Birk inhibitor… read more here.
Keywords: autophagy apoptosis; model alzheimer; vitro model; birk inhibitor ... See more keywords
Isolation, cultivation, and characterization of primary bovine cochlear pericytes: A new in vitro model of stria vascularis
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DOI: 10.1002/jcp.27545
Abstract: The study of strial pericytes has gained great interest as they are pivotal for the physiology of stria vascularis. To provide an easily accessible in vitro model, here we described a growth medium‐based approach to… read more here.
Keywords: primary bovine; vitro model; cochlear pericytes; physiology ... See more keywords
Limitations of an In Vitro Model of the Poultry Digestive Tract on the Evaluation of the Catalytic Performance of Phytases.
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DOI: 10.1002/jsfa.10878
Abstract: BACKGROUND The study aims to investigate the limitation of a poultry digestive tract model developed by Menezes-Blackburn et al.1 on the evaluation of the bioefficacy of phytases. RESULTS It was confirmed that the in vitro… read more here.
Keywords: model; digestive tract; poultry digestive; vitro model ... See more keywords
An In Vitro Model of Cellular Quiescence in Primary Human Dermal Fibroblasts.
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DOI: 10.1007/978-1-4939-7371-2_2
Abstract: Cellular quiescence is a reversible mode of cell cycle exit that allows cells and organisms to withstand unfavorable stress conditions. The factors that underlie the entry, exit, and maintenance of the quiescent state are crucial… read more here.
Keywords: human dermal; vitro model; quiescence; model cellular ... See more keywords
Development and validation of a new dynamic in vitro model of the piglet colon (PigutIVM): application to the study of probiotics
Sign Up to like & getrecommendations! Published in 2017 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-017-8122-y
Abstract: For ethical, technical, regulatory, and cost reasons, in vitro methods are increasingly used as an alternative to in vivo experimentations. The aim of the present study was to validate, according to in vivo data in… read more here.
Keywords: piglet colon; model piglet; vitro model;
Immunogenicity and antimicrobial effectiveness of Pseudomonas aeruginosa specific bacteriophage in a human lung in vitro model
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DOI: 10.1007/s00253-017-8504-1
Abstract: The rise of antibiotic resistant bacteria is posing a serious threat to human health. For example, resistant strains of Pseudomonas aeruginosa have resulted in untreatable and potentially lethal infections in both cystic fibrosis and immunocompromised… read more here.
Keywords: pseudomonas aeruginosa; vitro model; dms3; phage ... See more keywords
Calcium and zinc decrease intracellular iron by decreasing transport during iron repletion in an in vitro model
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DOI: 10.1007/s00394-017-1535-7
Abstract: PurposeIron is an essential micronutrient that participates in a number of vital reactions and its absorption may be altered by various nutritional factors such as other micronutrients. Our hypothesis is that iron absorption is decreased… read more here.
Keywords: vitro model; expression; calcium; iron ... See more keywords
Photobiomodulation increases cell viability via AKT activation in an in vitro model of diabetes induced by glucose neurotoxicity
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DOI: 10.1007/s10103-019-02808-2
Abstract: Peripheral neuropathy (PN) is a serious complication of diabetes mellitus (DM) and is known to be resistant to conventional treatment. Photobiomodulation (PBM) is demonstrated to be effective in treating PN and in protecting nerve fiber… read more here.
Keywords: induced glucose; vitro model; viability; neurotoxicity ... See more keywords