Optimization of micro-fabricated porous membranes for intestinal epithelial cell culture and in vitro modeling of the human intestinal barrier
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Micromechanics and Microengineering"
DOI: 10.1088/1361-6439/aa96bd
Abstract: In vitro modeling of organs could provide a controlled platform for studying physiological events and has great potential in the field of pharmaceutical development. Here, we describe the characterization of in vitro modeling of the… read more here.
Keywords: porous membranes; modeling human; intestinal barrier; vitro modeling ... See more keywords
In Vitro Modeling of Skin Barrier Disruption and its Recovery by Ceramide-Based Formulations.
Sign Up to like & getrecommendations! Published in 2021 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-021-02154-z
Abstract: Disrupted skin barrier, one of the severe attributes of inflammatory skin diseases, is caused by lower content and pathological changes of lipids in the uppermost skin layer-stratum corneum (SC). Restoring skin barrier with native skin… read more here.
Keywords: vitro models; barrier disruption; skin barrier; barrier ... See more keywords
A Bioreactor for 3D In Vitro Modeling of the Mechanical Stimulation of Osteocytes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.797542
Abstract: The bone is a mechanosensitive organ that is also a common metastatic site for prostate cancer. However, the mechanism by which the tumor interacts with the bone microenvironment to further promote disease progression remains to… read more here.
Keywords: bioreactor; vitro modeling; modeling mechanical; mechanical stimulation ... See more keywords
In vitro Modeling of Embryonal Tumors
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.640633
Abstract: A subset of pediatric tumors affects very young children and are thought to arise during fetal life. A common theme is that these embryonal tumors hijack developmental programs, causing a block in differentiation and, as… read more here.
Keywords: vitro modeling; biology; modeling embryonal; embryonal tumors ... See more keywords
Oxygen gradient generator to improve in vitro modeling of ischemic stroke
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2023.1110083
Abstract: Introduction In the core of a brain infarct, perfusion is severely impeded, and neuronal death occurs within minutes. In the penumbra, an area near the core with more remaining perfusion, cells initially remain viable, but… read more here.
Keywords: vitro modeling; oxygen gradient; generator; modeling ischemic ... See more keywords
Case Report: Precision Medicine Target Revealed by In Vitro Modeling of Relapsed, Refractory Acute Lymphoblastic Leukemia From a Child With Neurofibromatosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.851572
Abstract: Children with neurofibromatosis have a higher risk of developing juvenile myelomonocytic leukemia and acute myeloid leukemia, but rarely develop B-cell acute lymphoblastic leukemia (B-ALL). Through in-vitro modeling, a novel NF1 p.L2467 frameshift (fs) mutation identified… read more here.
Keywords: leukemia; vitro modeling; lymphoblastic leukemia; acute lymphoblastic ... See more keywords
Fracture Healing Research—Shift towards In Vitro Modeling?
Sign Up to like & getrecommendations! Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines9070748
Abstract: Fractures are one of the most frequently occurring traumatic events worldwide. Approximately 10% of fractures lead to bone healing disorders, resulting in strain for affected patients and enormous costs for society. In order to shed… read more here.
Keywords: towards vitro; vitro modeling; shift towards; fracture healing ... See more keywords