Insights into in vitro spermatogenesis in mammals: Past, present, future
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DOI: 10.1002/mrd.22819
Abstract: Considering the self‐renewal and differentiation ability of pluripotent stem cells, some studies have pointed out the possibility of stem cell‐derived sperm production. Most studies that test this hypothesis have been conducted on rodents, with some… read more here.
Keywords: spermatogenesis; stem cells; vitro spermatogenesis; insights vitro ... See more keywords
In vitro spermatogenesis: In search of fully defined conditions
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1106111
Abstract: A complete reconstruction of spermatogenesis in vitro under fully defined conditions still has not been achieved. However, many techniques have been proposed to get closer to that aim. Here we review the current progress in… read more here.
Keywords: fully defined; cell; defined conditions; search fully ... See more keywords
Understanding the Underlying Molecular Mechanisms of Meiotic Arrest during In Vitro Spermatogenesis in Rat Prepubertal Testicular Tissue
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23115893
Abstract: In vitro spermatogenesis appears to be a promising approach to restore the fertility of childhood cancer survivors. The rat model has proven to be challenging, since germ cell maturation is arrested in organotypic cultures. Here,… read more here.
Keywords: meiotic arrest; vitro spermatogenesis; rat prepubertal; prepubertal testicular ... See more keywords