Novel benzothiazole/benzothiazole thiazolidine‐2,4‐dione derivatives as potential FOXM1 inhibitors: In silico, synthesis, and in vitro studies
Sign Up to like & getrecommendations! Published in 2024 at "Archiv Der Pharmazie"
DOI: 10.1002/ardp.202400504
Abstract: The oncogenic transcription factor FOXM1 overexpressed in breast and other solid cancers, is a key driver of tumor growth and progression through complex interactions, making it an attractive molecular target for the development of targeted… read more here.
Keywords: vitro studies; novel benzothiazole; foxm1 inhibitors; foxm1 ... See more keywords
Comparative in vitro Studies of the Topoisomerase I Inhibition and Anticancer Activities of Metallated N‐Confused Porphyrins and Metallated Porphyrins
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DOI: 10.1002/cmdc.201900633
Abstract: Using the original approach, a series of metallated N‐confused porphyrins and metallated porphyrins have been synthesized and characterized. For all the synthesized porphyrins, in vitro studies of cytotoxic activity against K562, U937, HL‐60, Jurkat, A549 and… read more here.
Keywords: vitro studies; porphyrins metallated; metallated confused; inhibition ... See more keywords
A systematic review on neutrophils interactions with titanium and zirconia surfaces: Evidence from in vitro studies
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.582
Abstract: This systematic review aimed to assess in vitro studies that evaluated neutrophil interactions with different roughness levels in titanium and zirconia implant surfaces. read more here.
Keywords: titanium zirconia; vitro studies; systematic review;
Antimicrobial Peptide Moricin Inhibits Streptococcus pneumoniae Growth Through Membrane Disruption: Insights From In Silico and In Vitro Studies
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DOI: 10.1002/psc.70055
Abstract: The rise of multidrug‐resistant Streptococcus pneumoniae poses a major public health threat, necessitating novel therapeutic targets. Pneumococcal Surface Adhesin A (PsaA), a conserved surface lipoprotein, plays a key role in manganese acquisition, colonization and virulence.… read more here.
Keywords: membrane disruption; vitro studies; moricin; streptococcus pneumoniae ... See more keywords
Effects of selected alkaloids on postnatal neurogenesis - in vivo and in vitro studies - literature review
Sign Up to like & getrecommendations! Published in 2025 at "Psychopharmacology"
DOI: 10.1007/s00213-025-06856-1
Abstract: Postnatal neurogenesis is the process of new nerve cell formation that occurs after birth. The disruption of the neurogenesis process is a significant hypothesis in the development of mental disorders and diseases such as depression,… read more here.
Keywords: neurogenesis; vitro studies; selected alkaloids; vivo ... See more keywords
A review of in vivo and in vitro studies of the mare endometrium.
Sign Up to like & getrecommendations! Published in 2020 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2020.106605
Abstract: The inner layer of the uterus, the endometrium, is responsible and necessary for many reproductive functions. Normal reproductive cyclicity, maternal recognition of pregnancy, maternal interaction with the embryo, and interaction of the reproductive tract with… read more here.
Keywords: vivo vitro; review vivo; vitro studies; mare endometrium ... See more keywords
In Vitro Studies of the Folding and Assembly Mechanism of Hemoglobin
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DOI: 10.1016/j.bpj.2016.11.358
Abstract: Deriving the pathway for human hemoglobin assembly is important both for developing treatments for hemoglobinopathies and for designing robust acellular hemoglobin oxygen carriers. The adult human hemoglobin (HbA) comprises two globin heterodimers, (α1β1)(α2β2), with each… read more here.
Keywords: mechanism; hemoglobin; folding assembly; assembly mechanism ... See more keywords
In vitro studies of DNA condensation by bridging protein in a crowding environment.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2017.05.079
Abstract: The macromolecules of the bacterial cell occupy 20-40% of the total cytosol volume, and crowded environments have long been known to compact and stabilize DNA. Nevertheless, investigations on DNA-protein binding are generally performed in the… read more here.
Keywords: condensation; protein crowding; vitro studies; dna condensation ... See more keywords
In vitro studies of osteosarcoma: A researcher's perspective of quantity and quality
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DOI: 10.1016/j.jbo.2017.04.004
Abstract: Osteosarcoma is a primary malignant bone tumour, for which no improvement in survival rate has been made since the nineteen seventies. We set out to systemically identify the in vitro studies performed in the past… read more here.
Keywords: osteosarcoma researcher; perspective quantity; studies osteosarcoma; researcher perspective ... See more keywords
In vitro studies on anti-inflammatory activities of kiwifruit peel extract in human THP-1 monocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2018.12.044
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Kiwifruit is native to eastern China and many are the references about the consumption of fruits and fruits extracts of the Actinidia plants in Chinese traditional medicine as therapeutic food supplements to prevent… read more here.
Keywords: anti inflammatory; peel extract; kiwifruit peel; peel ... See more keywords
In vitro studies evaluating the efficacy of mouth rinses on Sars-Cov-2: A systematic review
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Infection and Public Health"
DOI: 10.1016/j.jiph.2021.07.020
Abstract: This systematic review aims to evaluate the efficacy of several mouth rinses on SARS-CoV-2 from in vitro studies. Five electronic databases were searched up to February 2021; no language or time restrictions were used. Two… read more here.
Keywords: rinses sars; systematic review; sars cov; vitro studies ... See more keywords