In Vitro Three-Dimensional Liver Models for Nanomaterial DNA Damage Assessment.
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DOI: 10.1002/smll.202006055
Abstract: Whilst the liver possesses the ability to repair and restore sections of damaged tissue following acute injury, prolonged exposure to engineered nanomaterials (ENM) may induce repetitive injury leading to chronic liver disease. Screening ENM cytotoxicity… read more here.
Keywords: dna damage; liver models; liver; assessment ... See more keywords
Development of in vitro three‐dimensional co‐culture system for metabolic syndrome therapeutic agents
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DOI: 10.1111/dom.13628
Abstract: There are many obstacles to overcome in the development of new drugs for metabolic diseases, including efficacy and toxicity problems in later stages of drug development. To overcome these problems and predict efficacy and toxicity… read more here.
Keywords: three dimensional; development vitro; dimensional culture; development ... See more keywords
An in vitro Three-Dimensional Co-Culture System for Ameloblastoma Modelling
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DOI: 10.17576/jsm-2019-4808-15
Abstract: Ameloblastoma, the most clinically significant odontogenic epithelial tumor, is a locally-invasive and destructive lesion in the jawbones. However, the nature of this infiltrativeness and destructive behavior remains ill-understood. To address this, we established an in… read more here.
Keywords: ameloblastoma; culture; cell; culture system ... See more keywords
Design of Hydrogel-based Scaffolds for in vitro Three-dimensional Human Skin Model Reconstruction.
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DOI: 10.2139/ssrn.4153561
Abstract: In vitro three-dimensional (3D) skin tissue models are critical tools in advancing our understanding of basic skin physiology and function as well as in specific applications such as toxicity testing of dermatological compounds. However, the… read more here.
Keywords: skin; vitro three; human skin; physiology ... See more keywords
Human iPS Cell-Derived Cell Aggregates Exhibited Dermal Papilla Cell Properties in in vitro Three-Dimensional Assemblage Mimicking Hair Follicle Structures
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DOI: 10.3389/fcell.2021.590333
Abstract: Current approaches for human hair follicle (HF) regeneration mostly adopt cell-autonomous tissue reassembly in a permissive murine intracorporeal environment. This, together with the limitation in human-derived trichogenic starting materials, potentially hinders the bioengineering of human… read more here.
Keywords: hair follicle; hair; cell aggregates; cell ... See more keywords
Current Research Trends in the Application of In Vitro Three-Dimensional Models of Liver Cells
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DOI: 10.3390/pharmaceutics15010054
Abstract: The liver produces and stores various nutrients that are necessary for the body and serves as a chemical plant, metabolizing carbohydrates, fats, hormones, vitamins, and minerals. It is also a vital organ for detoxifying drugs… read more here.
Keywords: culture; research trends; current research; vitro three ... See more keywords