Human papilloma virus vaccine and VITT antibody induction
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26659
Abstract: We recently reported on a 25-year-old female without a history of heparin exposure, presenting with thrombocytopenia, thrombosis, and elevated D-dimer levels 10 days after nine-valent human papillo-mavirus (HPV) vaccination ( Gardasil , Merck and Co).… read more here.
Keywords: vitt; vaccine vitt; papilloma virus; human papilloma ... See more keywords
Scientific premise for the involvement of neutrophil extracellular traps (NETs) in vaccine‐induced thrombotic thrombocytopenia (VITT)
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.5covr0621-320rr
Abstract: Following on from the devastating spread of COVID‐19, a major global priority has been the production, procurement, and distribution of effective vaccines to ensure that the global pandemic reaches an end. However, concerns were raised… read more here.
Keywords: induced thrombotic; thrombocytopenia; thrombocytopenia vitt; vitt ... See more keywords
Epidemiology of VITT
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in Hematology"
DOI: 10.1053/j.seminhematol.2022.02.002
Abstract: Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a life-threatening syndrome of aggressive thrombosis, often profound thrombocytopenia, and frequently overt disseminated intravascular coagulation. It has been associated with two adenovirus vector COVID-19 vaccines: ChAdOx1 nCoV-19 (AstraZeneca) and… read more here.
Keywords: vitt; chadox1 ncov; epidemiology vitt; case per ... See more keywords
Treatment of vaccine-induced immune thrombotic thrombocytopenia (VITT)
Sign Up to like & getrecommendations! Published in 2022 at "Seminars in Hematology"
DOI: 10.1053/j.seminhematol.2022.03.002
Abstract: Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a novel prothrombotic disorder characterized by thrombosis, thrombocytopenia, and disseminated intravascular coagulation identified in hundreds of recipients of ChAdOx1 nCoV-19 (Oxford/AstraZeneca), an adenovirus vector coronavirus disease 2019 (COVID-19) vaccine.… read more here.
Keywords: vitt; thrombocytopenia; vaccine induced; platelet ... See more keywords
Microsurgical complication associated with vaccine-induced immune thrombotic thrombocytopenia (VITT): A case report
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033013
Abstract: Rationale: The use of ChAdOx1 nCoV-19 (Astra Zeneca) vaccine has proven beneficial, but in a limited number of the general population, it was found to be associated with vaccine-induced immune thrombotic thrombocytopenia (VITT). However, there… read more here.
Keywords: vitt; chadox1 ncov; vaccine induced; associated vaccine ... See more keywords
Understanding vaccine‐induced thrombotic thrombocytopenia (VITT)
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DOI: 10.1111/imj.15783
Abstract: Vaccine‐induced thrombotic thrombocytopenia (VITT) is a rare, but serious, syndrome characterised by thrombocytopenia, thrombosis, a markedly raised D‐dimer and the presence of anti‐platelet factor‐4 (PF4) antibodies following COVID‐19 adenovirus vector vaccination. VITT occurs at a… read more here.
Keywords: vitt; thrombocytopenia vitt; induced thrombotic; vaccine induced ... See more keywords
Caution in Using the Activated Partial Thromboplastin Time to Monitor Argatroban in COVID-19 and Vaccine-Induced Immune Thrombocytopenia and Thrombosis (VITT)
Sign Up to like & getrecommendations! Published in 2021 at "Clinical and Applied Thrombosis/Hemostasis"
DOI: 10.1177/10760296211066945
Abstract: Introduction Argatroban is licensed for patients with heparin-induced thrombocytopenia and is conventionally monitored by activated partial thromboplastin time (APTT) ratio. The target range is 1.5 to 3.0 times the patients’ baseline APTT and not exceeding… read more here.
Keywords: time; thrombosis; covid; vitt ... See more keywords
A novel flow cytometry procoagulant assay for diagnosis of vaccine-induced immune thrombotic thrombocytopenia.
Sign Up to like & getrecommendations! Published in 2022 at "Blood advances"
DOI: 10.1182/bloodadvances.2021006698
Abstract: Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a severe prothrombotic complication of adenoviral vaccines, including ChAdOx1 nCoV-19 (Vaxzevria) vaccine. The putative mechanism involves formation of pathological anti-PF4 antibodies that activate platelets via the FcγRIIa receptor to… read more here.
Keywords: flow cytometry; induced immune; vitt; vaccine induced ... See more keywords
The deglycosylated form of 1E12 inhibits platelet activation and prothrombotic effects induced by VITT antibodies
Sign Up to like & getrecommendations! Published in 2022 at "Haematologica"
DOI: 10.3324/haematol.2021.280251
Abstract: In order to improve the safety of COVID-19 vaccines, there is an urgent need to unravel the pathogenesis of vaccine-induced immune thrombotic thrombocytopenia (VITT), a severe complication of recombinant adenoviral vector vaccines used to prevent… read more here.
Keywords: vitt; inhibits platelet; form 1e12; vitt antibodies ... See more keywords
Insights Into Immunothrombotic Mechanisms in Acute Stroke due to Vaccine-Induced Immune Thrombotic Thrombocytopenia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.879157
Abstract: During the COVID-19 pandemic, vaccination is the most important countermeasure. Pharmacovigilance concerns however emerged with very rare, but potentially disastrous thrombotic complications following vaccination with ChAdOx1. Platelet factor-4 antibody mediated vaccine-induced immune thrombotic thrombocytopenia (VITT)… read more here.
Keywords: vitt; immune thrombotic; patient; vaccine induced ... See more keywords
Thrombocytopenia in COVID-19 and vaccine-induced thrombotic thrombocytopenia
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Medicine"
DOI: 10.3892/ijmm.2022.5090
Abstract: The highly heterogeneous symptomatology and unpredictable progress of COVID-19 triggered unprecedented intensive biomedical research and a number of clinical research projects. Although the pathophysiology of the disease is being progressively clarified, its complexity remains vast.… read more here.
Keywords: vitt; induced thrombotic; covid; thrombocytopenia ... See more keywords