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Published in 2023 at "International journal of laboratory hematology"
DOI: 10.1111/ijlh.14075
Abstract: Platelet factor 4 (PF4, synonym: CXCL4) is an evolutionary old chemokine with proposed roles in hemostasis and antimicrobial defense. In addition, PF4 has attracted considerable attention as a crucial mediator of one of the most…
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Keywords:
hit vitt;
vitt antibodies;
pf4;
platelet ... See more keywords
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2
Published in 2022 at "Blood"
DOI: 10.1182/blood.2022017283
Abstract: Heparin-induced thrombocytopenia (HIT) is suspected much more often than it is confirmed. Technically-simple Platelet Factor-4 (PF4)-polyanion enzyme-linked immunosorbent assays (ELISAs) are sensitive but non-specific. In contrast, accurate functional tests such as the serotonin release assay,…
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Keywords:
hit vitt;
heparin;
vitt antibodies;
release ... See more keywords
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1
Published in 2022 at "Haematologica"
DOI: 10.3324/haematol.2021.280251
Abstract: In order to improve the safety of COVID-19 vaccines, there is an urgent need to unravel the pathogenesis of vaccine-induced immune thrombotic thrombocytopenia (VITT), a severe complication of recombinant adenoviral vector vaccines used to prevent…
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Keywords:
vitt;
inhibits platelet;
form 1e12;
vitt antibodies ... See more keywords