Tafenoquine: First Global Approval
Sign Up to like & getrecommendations! Published in 2018 at "Drugs"
DOI: 10.1007/s40265-018-0979-2
Abstract: Tafenoquine (Krintafel™, Arakoda™), an orally-active 8-aminoquinoline anti-malarial drug, is a long-acting analogue of primaquine with activity against pre-erythrocytic (liver) and erythrocytic (asexual) forms as well as gametocytes of Plasmodium species that include Plasmodium vivax (P.… read more here.
Keywords: vivax malaria; global approval; vivax; tafenoquine ... See more keywords
Therapeutic efficacy of chloroquine for the treatment of Plasmodium vivax malaria among outpatients at Shawa Robit Health Care Centre, North-East Ethiopia.
Sign Up to like & getrecommendations! Published in 2017 at "Acta tropica"
DOI: 10.1016/j.actatropica.2017.02.027
Abstract: Nearly 40% of all malaria infection in Ethiopia is caused by Plasmodium vivax. Chloroquine (CQ) is the first line treatment for confirmed P. vivax malaria in the country. However, the efficacy of this drug has… read more here.
Keywords: vivax malaria; therapeutic efficacy; study; vivax ... See more keywords
In silico analysis of putative dormancy genes in Plasmodium vivax.
Sign Up to like & getrecommendations! Published in 2018 at "Acta tropica"
DOI: 10.1016/j.actatropica.2018.06.026
Abstract: Plasmodium vivax is the most widely spread species causing human malaria. The control of malaria caused by P. vivax has been largely hampered by its ability to develop a dormant liver stage that can generate… read more here.
Keywords: putative dormancy; dormancy genes; dormancy; vivax ... See more keywords
Malaria transmission and individual variability of the naturally acquired IgG antibody against the Plasmodium vivax blood-stage antigen in an endemic area in Brazil.
Sign Up to like & getrecommendations! Published in 2020 at "Acta tropica"
DOI: 10.1016/j.actatropica.2020.105537
Abstract: Plasmodium vivax remains an important cause of malaria in South America and Asia, and analyses of the antibody immune response are being used to identify biomarker of parasite exposure. The IgG antibody naturally acquired predominantly… read more here.
Keywords: antibody; igg antibody; variability; malaria transmission ... See more keywords
Infection capacity of Trypanosoma vivax experimentally inoculated through different routes in bovines with latent Anaplasma marginale.
Sign Up to like & getrecommendations! Published in 2020 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2020.107861
Abstract: The aim of the present study was to compare the infection capacity of Trypanosoma vivax experimentally inoculated through different routes in calves naturally infected with latent Anaplasma marginale. On Day 0 of the study, 25… read more here.
Keywords: marginale; capacity trypanosoma; vivax; infection capacity ... See more keywords
Transcriptome and histone epigenome of Plasmodium vivax salivary-gland sporozoites point to tight regulatory control and mechanisms for liver-stage differentiation in relapsing malaria.
Sign Up to like & getrecommendations! Published in 2019 at "International journal for parasitology"
DOI: 10.1016/j.ijpara.2019.02.007
Abstract: Plasmodium vivax is the key obstacle to malaria elimination in Asia and Latin America, largely attributed to its ability to form resilient hypnozoites (sleeper cells) in the host liver that escape treatment and cause relapsing… read more here.
Keywords: vivax; plasmodium vivax; liver stage; liver ... See more keywords
The prevalence of molecular markers of drug resistance in Plasmodium vivax from the border regions of Thailand in 2008 and 2014
Sign Up to like & getrecommendations! Published in 2018 at "International Journal for Parasitology: Drugs and Drug Resistance"
DOI: 10.1016/j.ijpddr.2018.04.003
Abstract: The prevalence of Plasmodium vivax is increasing in the border regions of Thailand; one potential problem confounding the control of malaria in these regions is the emergence and spread of drug resistance. The aim of… read more here.
Keywords: drug resistance; vivax; resistance; border regions ... See more keywords
Plasmodium vivax pre-erythrocytic vaccines.
Sign Up to like & getrecommendations! Published in 2021 at "Parasitology international"
DOI: 10.1016/j.parint.2021.102411
Abstract: An estimated 229 million cases of malaria occurred worldwide in 2019. Both, Plasmodium falciparum and P. vivax are responsible for most of the malaria disease burden in the world. Despite difficulties in obtaining an accurate… read more here.
Keywords: vivax pre; vivax; plasmodium vivax; clinical trials ... See more keywords
Progress in understanding the phylogeny of Plasmodium vivax.
Sign Up to like & getrecommendations! Published in 2021 at "Parasitology international"
DOI: 10.1016/j.parint.2021.102507
Abstract: There has been some controversy about the evolutionary origin of Plasmodium vivax, particularly whether it is of Asian or African origin. Recently, a new malaria species which closely related to ape P. vivax was found… read more here.
Keywords: african origin; origin; vivax; plasmodium vivax ... See more keywords
Production of recombinant PvDBPII, receptor binding domain of Plasmodium vivax Duffy binding protein, and evaluation of immunogenicity to identify an adjuvant formulation for vaccine development.
Sign Up to like & getrecommendations! Published in 2017 at "Protein expression and purification"
DOI: 10.1016/j.pep.2015.06.011
Abstract: Plasmodium vivax is dependent on interaction with the Duffy antigen receptor for chemokines (DARC) for invasion of human erythrocytes. The P. vivax Duffy binding protein (PvDBP) mediates interaction of P. vivax merozoites with DARC. The DARC receptor-binding… read more here.
Keywords: recombinant pvdbpii; vaccine; pvdbpii; vivax ... See more keywords
Plasmodium vivax in Hematopoietic Niches: Hidden and Dangerous.
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DOI: 10.1016/j.pt.2020.03.002
Abstract: Estimation of Plasmodium vivax biomass based on circulating biomarkers indicates the existence of a predominant biomass outside of the circulation that is not captured by peripheral parasitemia, in particular in patients with complicated outcomes. A… read more here.
Keywords: vivax hematopoietic; niches hidden; vivax; plasmodium vivax ... See more keywords