Overexpression of UCP3 decreases mitochondrial efficiency in mouse skeletal muscle in vivo
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14494
Abstract: Uncoupling protein‐3 (UCP3) is a mitochondrial transmembrane protein highly expressed in the muscle that has been implicated in regulating the efficiency of mitochondrial oxidative phosphorylation. Increasing UCP3 expression in skeletal muscle enhances proton leak across… read more here.
Keywords: overexpression ucp3; vivo; muscle; efficiency ... See more keywords
Development and Preliminary In Vivo Study of 3D‐Printed Bioactive Glass Scaffolds with Trabecular Architecture
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Engineering Materials"
DOI: 10.1002/adem.202501569
Abstract: The bioactive silicate glass “1d” (BG‐1d), belonging to the multicomponent CaO–MgO–Na2O–P2O5–SiO2–CaF2 system, is proved to be highly effective in promoting alveolar bone regeneration in humans when implanted in the form of particles. This study moves… read more here.
Keywords: vivo; glass; development preliminary; scaffolds trabecular ... See more keywords
Multifunctional Glyco-Nanofibers: siRNA Induced Supermolecular Assembly for Codelivery In Vivo
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Functional Materials"
DOI: 10.1002/adfm.201703083
Abstract: Targeted codelivery and controlled release of drug/siRNA (small interfering RNA) in a safe and effective vehicle hold great promises for overcoming drug resistance and optimal efficacy in cancer treatment; however, rational design and preparation of… read more here.
Keywords: glyco nanofibers; supermolecular assembly; codelivery; vivo ... See more keywords
Self‐Aggregated Carbon Dots Enable High‐Contrast NIR‐II In Vivo Bioimaging
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202523460
Abstract: Carbon dots (CDs), particularly those with dimensions below 5 nm, exhibit unique tissue‐penetrating capabilities, enabling them to traverse subcellular compartments and cross microbial membranes. However, they suffer from rapid renal clearance via glomerular filtration, which results… read more here.
Keywords: carbon; carbon dots; vivo; self aggregated ... See more keywords
Ultrasensitive NIR‐SERRS Probes with Multiplexed Ratiometric Quantification for In Vivo Antibody Leads Validation
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201700870
Abstract: Immunotargeting ability of antibodies may show significant difference between in vitro and in vivo. To select antibody leads with high affinity and specificity, it is necessary to perform in vivo validation of antibody candidates following… read more here.
Keywords: validation; vivo; nir serrs; antibody ... See more keywords
Using Ultrafast Responsive Phosphorescent Nanoprobe to Visualize Elevated Peroxynitrite In Vitro and In Vivo via Ratiometric and Time‐Resolved Photoluminescence Imaging
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.201800309
Abstract: Peroxynitrite (ONOO- ), a potent biological oxidant, which has a short half-life in physiological conditions, is related to many diseases. Accurate peroxynitrite determination with superior selectivity and sensitivity is important for understanding biological roles of… read more here.
Keywords: photoluminescence imaging; time resolved; vivo via; vivo ... See more keywords
A Facile, Protein‐Derived Supramolecular Theranostic Strategy for Multimodal‐Imaging‐Guided Photodynamic and Photothermal Immunotherapy In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202109111
Abstract: Theranostic systems that permit both diagnosis and treatment in vivo are highly appealing means by which to meet the demands of precision medicine. However, most such systems remain subject to issues related to complex molecular… read more here.
Keywords: vivo; supramolecular theranostic; strategy; photodynamic photothermal ... See more keywords
An Implantable Magnetic Vascular Scaffold for Circulating Tumor Cell Removal In Vivo
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202207870
Abstract: An integrated trapped device (ITD) capable of removal of circulating tumor cells (CTCs) can assuage or even prevent metastasis. However, adhesion repertoires are ordinarily neglected in the design of ITDs, possibly leading to the omission… read more here.
Keywords: circulating tumor; vascular; itd; vivo ... See more keywords
Engineering and Development of a Tissue Model for the Evaluation of Microneedle Penetration Ability, Drug Diffusion, Photothermal Activity, and Ultrasound Imaging: A Promising Surrogate to Ex Vivo and In Vivo Tissues
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202210034
Abstract: Driven by regulatory authorities and the ever‐growing demands from industry, various artificial tissue models have been developed. Nevertheless, there is no model to date that is capable of mimicking the biomechanical properties of the skin… read more here.
Keywords: diffusion; vivo; evaluation microneedle; model ... See more keywords
Upconversion 3D Bioprinting for Noninvasive In Vivo Molding
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DOI: 10.1002/adma.202310617
Abstract: Tissue engineered bracket materials provide essential support for the physiological protection and therapeutics of patients. Unfortunately, the implantation process of such devices poses the risk of surgical complications and infection. In this study, an upconversion… read more here.
Keywords: vivo molding; bioprinting noninvasive; noninvasive vivo; vivo ... See more keywords
Achieving High‐Brightness NIR‐II Emission: Molecular Locking and Wrapping Strategies in Fluorescent Material Design for in Vivo Bioimaging
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Materials"
DOI: 10.1002/adma.202510386
Abstract: Near‐infrared‐II (NIR‐II) fluorescence imaging has transformed biomedical imaging by providing low autofluorescence, deep tissue penetration, and superior spatial resolution, essential for precise in vivo biological visualization. However, developing NIR‐II‐emitting molecular fluorophores with high brightness remains… read more here.
Keywords: high brightness; brightness; vivo; fluorescence ... See more keywords