Oxidation Products from the Neolignan Licarin A by Biomimetic Reactions and Assessment of in vivo Acute Toxicity
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DOI: 10.1055/a-2009-0732
Abstract: Abstract Licarin A, a dihydrobenzofuranic neolignan presents in several medicinal plants and seeds of nutmeg, exhibits strong activity against protozoans responsible for Chagas disease and leishmaniasis. From biomimetic reactions by metalloporphyrin and Jacobsen catalysts, seven… read more here.
Keywords: biomimetic reactions; toxicity; acute toxicity; vivo acute ... See more keywords
In Vivo Acute Toxicity Studies of Novel Anti-Melanoma Compounds Downregulators of hnRNPH1/H2
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DOI: 10.3390/biom13020349
Abstract: Despite the recent advances in melanoma therapy, the need for new targets and novel approaches to therapy is urgent. We previously reported melanoma actives that work via binding and downregulating spliceosomal proteins hnRNPH1 and H2.… read more here.
Keywords: melanoma; chemistry; acute toxicity; vivo acute ... See more keywords
In Vivo Acute Toxicity and Immunomodulation Assessment of a Novel Nutraceutical in Mice
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DOI: 10.3390/pharmaceutics15041292
Abstract: Achieving and maintaining a well-balanced immune system has righteously become an insightful task for the general population and an even more fundamental goal for those affected by immune-related diseases. Since our immune functions are indispensable… read more here.
Keywords: acute toxicity; novel nutraceutical; vivo acute; mice ... See more keywords