In Vitro and In Vivo Antimicrobial Activity of Antibiotic-Conjugated Carriers with Rapid pH-Responsive Release Kinetics.
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DOI: 10.1002/adhm.201900247
Abstract: Two representative antibiotics, cephradine (CP) and moxifloxacin (MX), are covalently conjugated with a β-cyclodextrin (β-CD)-based carrier via pH-responsive 1-methyl-2-(2'-carboxyethyl) maleic acid amide (MCM) linkers with excellent conjugation efficiency via simple mixing. At pH 5.5, 90%… read more here.
Keywords: vitro vivo; antimicrobial activity; activity antibiotic; vivo antimicrobial ... See more keywords
Bilosomes as Nanoplatform for Oral Delivery and Modulated In Vivo Antimicrobial Activity of Lycopene
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DOI: 10.3390/ph15091043
Abstract: Owing to the disseminating resistance among pathogenic bacteria, especially Klebsiella pneumoniae, there is a high need for alternate compounds with antibacterial activity. Herein, lycopene was isolated from Lycopersicon esculentum L. Molecular docking approach was employed… read more here.
Keywords: vivo antimicrobial; antimicrobial activity; activity; lycopene ... See more keywords