Non-invasive monitoring of in vivo bone regeneration based on alkaline phosphatase-responsive scaffolds
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DOI: 10.1016/j.cej.2020.127959
Abstract: Abstract Although numerous biomaterials are fabricated as scaffolds for the application of tissue engineering, real-time non-invasive monitoring of in vivo bone regeneration is still a big challenge. Especially during early osteogenesis, which is difficult to… read more here.
Keywords: invasive monitoring; bone regeneration; monitoring vivo; vivo bone ... See more keywords
The mineralization, drug release and in vivo bone defect repair properties of calcium phosphates/PLA modified tantalum scaffolds
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DOI: 10.1039/c9ra09385k
Abstract: Calcium phosphate based biomaterials have been widely studied in biomedical areas. Herein, amorphous calcium phosphate (ACP) nanospheres and hydroxyapatite (HA) nanorods were separately prepared and used for coating tantalum (Ta) scaffolds with a polymer of… read more here.
Keywords: pla; coated scaffolds; vivo bone; bone defect ... See more keywords
FITC-Labeled Alendronate as an In Vivo Bone pH Sensor
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DOI: 10.1155/2020/4012194
Abstract: pH is a critical indicator of bone physiological function and disease status; however, noninvasive and real-time sensing of bone pH in vivo has been a challenge. Here, we synthesized a bone pH sensor by labeling… read more here.
Keywords: bone sensor; vivo bone; fitc; bone ... See more keywords
A Novel Ex Vivo Bone Culture Model for Regulation of Collagen/Apatite Preferential Orientation by Mechanical Loading
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DOI: 10.3390/ijms23137423
Abstract: The anisotropic microstructure of bone, composed of collagen fibers and biological apatite crystallites, is an important determinant of its mechanical properties. Recent studies have revealed that the preferential orientation of collagen/apatite composites is closely related… read more here.
Keywords: vivo bone; mechanical loading; collagen; collagen apatite ... See more keywords
In Vivo Bone Tissue Engineering Strategies: Advances and Prospects
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DOI: 10.3390/polym14153222
Abstract: Reconstruction of critical-sized bone defects remains a tremendous challenge for surgeons worldwide. Despite the variety of surgical techniques, current clinical strategies for bone defect repair demonstrate significant limitations and drawbacks, including donor-site morbidity, poor anatomical… read more here.
Keywords: tissue engineering; bone; bone tissue; vivo bone ... See more keywords