In vivo Environment Swiftly Restricts Human Pancreatic Progenitors Toward Mono-Hormonal Identity via a HNF1A/HNF4A Mechanism
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DOI: 10.3389/fcell.2020.00109
Abstract: Generating insulin-producing β-cells from human induced pluripotent stem cells is a promising cell replacement therapy for improving or curing insulin-dependent diabetes. The transplantation of end-stages differentiating cells into living hosts was demonstrated to improve β-cell… read more here.
Keywords: human pancreatic; vivo environment; hnf1a hnf4a; identity ... See more keywords