In vivo evaluation of population‐specific inversion pulses in parallel transmission
Sign Up to like & getrecommendations! Published in 2025 at "Magnetic Resonance in Medicine"
DOI: 10.1002/mrm.30593
Abstract: The aim of the study was to conduct in vivo evaluation of population‐specific pulses in the context of the MP2RAGE sequence for brain imaging at 7T. read more here.
Keywords: vivo evaluation; population specific; specific inversion; evaluation population ... See more keywords
Matrigel Plug Assay for In Vivo Evaluation of Angiogenesis.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9133-4_18
Abstract: Matrigel is extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma in C57BL/6 mice, a tumor rich in extracellular matrix (ECM) proteins. It consists mainly of laminin (approximately 60%), collagen IV (approximately 30%), and nidogen-1/entactin (approximately 8%),… read more here.
Keywords: matrigel plug; assay vivo; angiogenesis; matrigel ... See more keywords
Optimization, characterization and in vitro/vivo evaluation of azilsartan nanocrystals
Sign Up to like & getrecommendations! Published in 2017 at "Asian Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ajps.2016.09.008
Abstract: Graphical Abstract Through formulation screening, the irregular-shaped azilsartan nanocrystals were prepared and optimized by bead milling method and solidified by freeze-drying. The best formulation which had the size of 300 nm was expressed in its state… read more here.
Keywords: vitro vivo; azilsartan nanocrystals; azilsartan; characterization vitro ... See more keywords
Sertaconazole nitrate loaded nanovesicular systems for targeting skin fungal infection: In-vitro, ex-vivo and in-vivo evaluation.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2017.05.029
Abstract: The aim of this study was to develop different vesicular systems for sertaconazole nitrate and evaluate the ability of targeting deep skin layers to treat dermal fungal infection. Therefore, different phospholipid based nanovesicles, namely liposomes,… read more here.
Keywords: vivo; fungal infection; infection; study ... See more keywords
In vitro and in vivo evaluation of pterostilbene for the management of diabetic complications
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Ayurveda and Integrative Medicine"
DOI: 10.1016/j.jaim.2018.01.003
Abstract: Background Aldose reductase (AR) and Advanced glycation end product (AGE) are known to play important roles in the development of diabetic complications. The inhibitors of AR and AGE would be potential agents for the prevention… read more here.
Keywords: pterostilbene management; evaluation pterostilbene; vitro vivo; pterostilbene ... See more keywords
In-situ gel of nifedipine for preeclampsia: Optimization, in-vitro and in-vivo evaluation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2019.01.025
Abstract: Abstract Present study was conducted to develop and optimize in-situ gel for sustained delivery of Nifedipine by ion sensitive mechanism and its in-vitro and in-vivo evaluation. Factorial design was employed to evaluate the effect of… read more here.
Keywords: vivo evaluation; situ; preeclampsia; situ gel ... See more keywords
The ability of tanniniferous legumes to reduce methane production and enhance feed utilization in Barki rams: in vitro and in vivo evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Small Ruminant Research"
DOI: 10.1016/j.smallrumres.2020.106259
Abstract: Abstract Two experiments (in vitro and in vivo evaluation) were conducted to evaluate the ability of three different tanniniferous legumes to replace berseem hay on ruminal fermentation, digestibility and methane (CH4) emission. Berseem (Trifolium alexandrinum… read more here.
Keywords: tanniniferous legumes; vitro vivo; evaluation; vivo evaluation ... See more keywords
In silico, in vitro and in vivo evaluation of natural Bignoniaceous naphthoquinones in comparison with atovaquone targeting the selection of potential antimalarial candidates.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2020.115074
Abstract: The natural naphthoquinones lapachol, α- and β-lapachone are found in Bignoniaceous Brazilian plant species of the Tabebuia genus (synonym Handroanthus) and are recognized for diverse bioactivities, including as antimalarial. The aim of the present work… read more here.
Keywords: vitro vivo; naphthoquinones comparison; comparison atovaquone; vivo evaluation ... See more keywords
Design, Synthesis, and In Vivo Evaluation of Isosteviol Derivatives as New SIRT3 Activators with Highly Potent Cardioprotective Effects.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.4c00345
Abstract: Cardiovascular diseases (CVDs) persist as the predominant cause of mortality, urging the exploration of innovative pharmaceuticals. Mitochondrial dysfunction stands as a pivotal contributor to CVDs development. Sirtuin 3 (SIRT3), a prominent mitochondrial deacetylase known for… read more here.
Keywords: evaluation isosteviol; vivo; vivo evaluation; sirt3 activators ... See more keywords
From Dynamic Combinatorial Chemistry to in Vivo Evaluation of Reversible and Irreversible Myeloperoxidase Inhibitors.
Sign Up to like & getrecommendations! Published in 2017 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.6b00417
Abstract: The implementation of dynamic combinatorial libraries allowed the determination of highly active reversible and irreversible inhibitors of myeloperoxidase (MPO) at the nanomolar level. Docking experiments highlighted the interaction between the most active ligands and MPO,… read more here.
Keywords: dynamic combinatorial; combinatorial chemistry; chemistry; vivo evaluation ... See more keywords
Synthesis, in vitro, and in vivo evaluation of novel N-phenylindazolyl diarylureas as potential anti-cancer agents
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-74572-1
Abstract: Novel N-phenylindazole based diarylureas have been designed, synthesized and evaluated as potential anticancer agents. In vitro cell viability studies of these derivatives illustrate good potency with IC50 values in the range of 0.4–50 μM in… read more here.
Keywords: evaluation novel; novel phenylindazolyl; vitro vivo; synthesis vitro ... See more keywords