The in vivo genetic toolkit for studying expression and functions of Drosophila melanogaster microRNAs
Sign Up to like & getrecommendations! Published in 2017 at "RNA Biology"
DOI: 10.1080/15476286.2016.1272748
Abstract: ABSTRACT Since the initial reports that a group of small RNAs, now known as microRNAs (miRNAs), regulates gene expression without being translated into proteins, there has been an explosion of studies on these important expression… read more here.
Keywords: toolkit studying; genetic toolkit; drosophila melanogaster; vivo genetic ... See more keywords
PertOrg 1.0: a comprehensive resource of multilevel alterations induced in model organisms by in vivo genetic perturbation
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac872
Abstract: Abstract Genetically modified organisms (GMOs) can be generated to model human genetic disease or plant disease resistance, and they have contributed to the exploration and understanding of gene function, physiology, disease onset and drug target… read more here.
Keywords: multilevel alterations; model organisms; pertorg; genetic perturbation ... See more keywords
An in vivo genetic screen for genes involved in spliced leader trans-splicing indicates a crucial role for continuous de novo spliced leader RNP assembly
Sign Up to like & getrecommendations! Published in 2017 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx500
Abstract: Abstract Spliced leader (SL) trans-splicing is a critical element of gene expression in a number of eukaryotic groups. This process is arguably best understood in nematodes, where biochemical and molecular studies in Caenorhabditis elegans and… read more here.
Keywords: leader trans; spliced leader; vivo genetic; role ... See more keywords