Genotoxicity from metronidazole detected in vitro, but not in vivo, in healthy dogs in a randomized clinical trial.
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DOI: 10.2460/ajvr.22.07.0112
Abstract: OBJECTIVE To determine whether metronidazole (MTZ), at recommended therapeutic dosages in dogs, induces peripheral blood cell (PMBC) genotoxicity, using the γ-H2AX assay as a sensitive measure of DNA breaks. The secondary aim was to assess… read more here.
Keywords: healthy dogs; dna; vivo healthy; mtz ... See more keywords