Articles with "vivo investigation" as a keyword



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In Vivo Investigation of Glucose Metabolism in Idiopathic and PRKN‐Related Parkinson's Disease

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Published in 2023 at "Movement Disorders"

DOI: 10.1002/mds.29333

Abstract: Alterations in mitochondrial dysfunction have been implicated in the pathogenesis of Parkinson's disease (PD). Mitochondrial energy production is linked to glucose metabolism, and diabetes is associated with PD. However, studies investigating glucose metabolism in vivo… read more here.

Keywords: metabolism; investigation glucose; parkinson disease; vivo investigation ... See more keywords
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Ex Vivo Investigation of Bexarotene and Nicotinamide Function as a Protectıve Agent on Rat Synaptosomes Treated with Aβ(1-42).

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Published in 2021 at "Neurochemical research"

DOI: 10.1007/s11064-020-03216-7

Abstract: In this study, we were aimed to investigate the neuroprotective effects of bexarotene and nicotinamide in synaptosomes incubated with amyloid-beta (Aβ). Our study consists of 2 parts, in vivo and in vitro. In the in… read more here.

Keywords: bexarotene nicotinamide; vivo investigation; investigation bexarotene; bexarotene ... See more keywords
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In vitro antioxidant assay guided ex vivo investigation of cytotoxic effect of phytosomes assimilating taxifolin rich fraction of Cedrus deodara bark extract on human breast cancer cell lines (MCF7)

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Published in 2021 at "Journal of Drug Delivery Science and Technology"

DOI: 10.1016/j.jddst.2021.102486

Abstract: Abstract Objective Characterization, in vitro evaluation of antioxidant activity and ex vivo investigation of cytotoxic effect of phytosomes assimilating ethyl acetate fraction fractionated from hydro alcoholic extract of Cedrus deodara bark. Method Solvent fractions of… read more here.

Keywords: investigation cytotoxic; investigation; ethyl acetate; fraction ... See more keywords
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In vitro and in vivo investigation of cardiotoxicity associated with anticancer proteasome inhibitors and their combination with anthracycline.

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Published in 2019 at "Clinical science"

DOI: 10.1042/cs20190139

Abstract: Although proteasome inhibitors (PIs) are modern targeted anticancer drugs, they have been associated with a certain risk of cardiotoxicity and heart failure (HF). Recently, PIs have been combined with anthracyclines to further boost their anticancer… read more here.

Keywords: proteasome inhibitors; investigation cardiotoxicity; vitro vivo; vivo investigation ... See more keywords
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In vivo investigation of antihyperalgesic and antinociceptive effects of peat formulations

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Published in 2018 at "Acta Pharmaceutica"

DOI: 10.2478/acph-2018-0029

Abstract: Abstract The aim of this study is to evaluate the antihyperalgesic and antinociceptive effects of two formulations containing peat water extracts using a model of carrageenan-induced hyperalgesia, combined with a test with a mechanical stimulus,… read more here.

Keywords: basis creme; wolff basis; antinociceptive effects; vivo investigation ... See more keywords